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Joint effect of occupational ionizing radiation and cigarette smoking on lung cancer mortality in the US radiologic technologists
https://repo.qst.go.jp/records/65213
https://repo.qst.go.jp/records/65213cba58aff-d91f-48e3-b2e9-7d3628b6b17a
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-10-22 | |||||
| タイトル | ||||||
| タイトル | Joint effect of occupational ionizing radiation and cigarette smoking on lung cancer mortality in the US radiologic technologists | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Doi, Kazutaka
× Doi, Kazutaka× et.al× 土居 主尚 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Lung cancer has been associated with high doses of radiation. Studies of populations with low, protracted exposures have provided little or inconsistent evidence of a dose-response, possibly due to difficulty in taking into account the effect of cigarette smoking, which may confound or interact with radiation exposure. While the joint effect of radiation and smoking has been well investigated in several studies, there is limited information about the joint effect of chronic low LET radiation exposure and smoking. We examined lung cancer mortality risk among 106,029 US radiologic technologists who were cancer-free at a baseline questionnaire with follow-up from the baseline questionnaire until the end of 2007. The average follow-up was 20.7 years and there were 843 lung cancer deaths. Cumulative lung doses (mean 0.017, range 0-0.81Gy) were estimated using a Monte Carlo dosimetry system. Poisson regression models for excess relative risk (ERR) were employed to examine the joint effect of radiation and smoking, adjusted for age, sex, birth year and race. Multiplicative and additive interaction forms were compared using the AIC. An ERR model with additive interaction fit best. The ERR per Gy for lung cancer mortality was estimated to be 10.94 (-2.57, 24.46) and the ERR per 20 pack-years of cigarettes smoked, 1.10 (0.41, 1.79). | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 日本放射線影響学会第56会大会 | |||||
| 発表年月日 | ||||||
| 日付 | 2013-10-20 | |||||
| 日付タイプ | Issued | |||||
