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Radiotherapy concurrently with weekly cisplatin followed by adjuvant chemotherapy for N2-3 nasopharyngeal cancer: Multicenter trial of the Forum for Nuclear Cooperation in Asia (FNCA)
https://repo.qst.go.jp/records/64917
https://repo.qst.go.jp/records/649174317a1a6-f8f5-47ed-bc07-214e200f6820
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-02-12 | |||||
| タイトル | ||||||
| タイトル | Radiotherapy concurrently with weekly cisplatin followed by adjuvant chemotherapy for N2-3 nasopharyngeal cancer: Multicenter trial of the Forum for Nuclear Cooperation in Asia (FNCA) | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
大野, 達也
× 大野, 達也× 加藤, 真吾× 若月, 優× 唐澤, 久美子× 中野, 隆史× 辻井, 博彦× 大野 達也× 加藤 眞吾× 若月 優× 唐澤 久美子× 辻井 博彦 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | (Purpose) To evaluate the toxicity and efficacy of radiotherapy concurrently with weekly cisplatin follow-ed by adjuvant chemotherapy for N2-3 nasopharyngeal cancer. \n(Materials and Methods) Between 2005 and 2009, 121 patients with nasopharyngeal cancer (T1-4 N2-3 M0) were registered from Viet Nam, Malaysia, Indonesia, Thailand, The Philippines, China and Bangladesh. Patients were treated with 2-dimensional radiotherapy concurrently with weekly cisplatin (30mg/m2) followed by adjvant chemotherapy consisting of cisplatin (80mg/m2 on Day 1) and fluorouracil (800mg/m2 on Days 1_5) for three cycles. \n(Results) Ninety-three percent of the patients completed at least 4 cycles of weekly cisplatin during radiotherapy, and 82% completed at least 2 cycles of adjvant chemotherapy. Complete response was obtained in 95% of the patients. With a median follow-up time of 46 months for the survival, and overall survival rated were 75%, 65%, and 52%, respectively. No treatment-related deaths occurred. Grade 3-4 toxicities of mucositis, nausea/vomiing, and leukopenia were observed in 34% , 4%, and 4% of the patients, respectively. \n(Conclusion) The current results showed that concurrent chemoradiotherapy followed by adjuvant chemotherapy of our regimen was safe and effective in the participating institutes. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 日本放射線腫瘍学会第25回学術大会 | |||||
| 発表年月日 | ||||||
| 日付 | 2012-11-25 | |||||
| 日付タイプ | Issued | |||||
