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In-Beam Imaging Performance of the Small OpenPET Prototype With <sup>10</sup>C Beam Irradiation
https://repo.qst.go.jp/records/64385
https://repo.qst.go.jp/records/64385c3190a68-fd32-42b9-a406-d5ec765a2cc8
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2011-11-08 | |||||
| タイトル | ||||||
| タイトル | In-Beam Imaging Performance of the Small OpenPET Prototype With <sup>10</sup>C Beam Irradiation | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Yamaya, Taiga
× Yamaya, Taiga× et.al× 山谷 泰賀 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The OpenPET geometry is our original idea to visualize a physically opened space between two detector rings. One of our targets is in-beam PET, which is a method for <i>in situ</i> monitoring of charged particle therapy. We expect the OpenPET geometry will be the first practical 3D geometry to be realized, as conventional systems using positron cameras are basically limited to 2D imaging with low statistics. For the usual carbon (<sup>12</sup>C) beam irradiation, the activity of produced positron emitters is generally low, in addition to there being a theoretical difference between the dose distribution and positron emitter distribution. Therefore direct irradiation of radioactive beams is ideal for in-beam PET. At this stage, we have developed a small prototype to show a proof-of-concept of the OpenPET imaging, and carried out the initial in-beam tests in the Heavy Ion Medical Accelerator in Chiba (HIMAC). In this paper, we focused on utilization of a <sup>10</sup>C radioactive beam, whose half-life is about 19 s, and we evaluated in-beam imaging performance of the small OpenPET prototype using <sup>10</sup>C, <sup>11</sup>C and <sup>12</sup>C beams. The OpenPET prototype was positioned so that the beam passed through the gap. A rectangular parallelepiped PMMA phantom was placed in the center of the FOV. The <sup>11</sup>C beam and the <sup>10</sup>C beam were generated as secondary beams from the <sup>12</sup>C beam. Imaging results showed that PET images directly corresponding to the distribution of primary particles were obtained by the radioactive beam irradiation. In particular, a much higher activity concentration was seen in the <sup>10</sup>C beam irradiation than that in the <sup>11</sup>C beam irradiation. For 3 Gy irradiation of the <sup>10</sup>C beam, the 3D distribution of the primary particles in the phantom was clearly visualized from only in-beam PET measurements without any additional PET measurements. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | The 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference | |||||
| 発表年月日 | ||||||
| 日付 | 2011-10-29 | |||||
| 日付タイプ | Issued | |||||
