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重粒子線治療における酸化ストレスおよび抗酸化力に関する研究
https://repo.qst.go.jp/records/64151
https://repo.qst.go.jp/records/641510d031dac-7d5e-41a9-ac01-fa9556ea03b8
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2010-12-14 | |||||
| タイトル | ||||||
| タイトル | 重粒子線治療における酸化ストレスおよび抗酸化力に関する研究 | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
山田, 滋
× 山田, 滋× 山田, 泰寿× 清水, 一範× 篠藤, 誠× 安藤, 興一× 山田 滋× 山田 泰寿× 清水 一範× 篠藤 誠× 安藤 興一 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Oxygen is required for respriration and the energetic processes that enable aerobic life. Free radical and reactive oxygen matabolite (ROM) formations create oxidative stress and contribute to various processes including aging, degenerative diseases and cancer. Additionally, they may have a role in the radiotherapy for various types of cancer. In this study, we aimed to investigate the degree of oxidative stress for carbon-ion radiotherapy in locally recurrent rectal cancer and pancreas cancer, and to find out whether the degree of oxidative stress shows any difference among different grade of normal tissue damages. It can be used as an index for their differential diagnosis. Sixteen patients with locally recurrent rectal cancer and 6 pancreas cancers were included in the study. The BAP levels were lower before carbon-ion treatment than after treatment. The ROM levels were significantly lower before treatment than after treatment. It might be possible to conclude that the serum BAP and ROM levels may be an index parameter for normal tissue damages. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 平成21年度HIMC共同利用研究成果発表会 | |||||
| 発表年月日 | ||||||
| 日付 | 2010-04-20 | |||||
| 日付タイプ | Issued | |||||
