WEKO3
アイテム
重粒子線と化学療法の併用療法における脳正常組織および神経膠芽腫の放射線感受性の検討
https://repo.qst.go.jp/records/63624
https://repo.qst.go.jp/records/63624bb71623c-14dc-4399-bf56-e533935b0bbe
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2009-10-07 | |||||
| タイトル | ||||||
| タイトル | 重粒子線と化学療法の併用療法における脳正常組織および神経膠芽腫の放射線感受性の検討 | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
吉田, 由香里
× 吉田, 由香里× 清原, 浩樹× 加藤, 弘之× 石内, 勝吾× 鈴木, 義行× 加藤, 真吾× 中野, 隆史× 吉田 由香里× 清原 浩樹× 加藤 弘之× 鈴木 義行× 加藤 眞吾× 中野 隆史 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Glioblastoma (GBM) is one of the most common and the most malignant tumor occurring in the central nervous system. GBM is notorious for highly growth and invasive behavior and makes the surgical intervention ineffective. Recently, though there are many reports about the effectiveness of carbon ion therapy, little is known about effects of carbon ion therapy for GBM. In addition, the almost of GBM patients has not satisfied with treatment of the carbon ion alone for GBM. Temozolomide (TMZ) is a cytotoxic alkylating agent which has shown an activity in the recurrent anaplastic glioma and GBM. Combining TMZ with radiotherapy followed by maintenance TMZ has been reported to improve outcome compared with radiation alone, and this treatment is currently considered as the standard treatment for GBM. Hence, in this study, we investigated the effectiveness of combining TMZ with carbon ion therapy for GBM. The addition of TMZ to carbon ion therapy was significantly decreased the tumor growth in compared to the carbon ion alone for in vitro and in vivo experiments. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | H20年度HIMAC共同利用研究 成果発表会 | |||||
| 発表年月日 | ||||||
| 日付 | 2009-04-14 | |||||
| 日付タイプ | Issued | |||||
