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Paroxetine induced psychose - activation syndrome with distinct psychotic feature -

https://repo.qst.go.jp/records/63217
https://repo.qst.go.jp/records/63217
0fe6ea3f-be0f-4a4b-9cd5-98916942d46f
Item type 会議発表用資料 / Presentation(1)
公開日 2009-09-07
タイトル
タイトル Paroxetine induced psychose - activation syndrome with distinct psychotic feature -
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Saio, Takeo

× Saio, Takeo

WEKO 624339

Saio, Takeo

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Kurihara, Chieko

× Kurihara, Chieko

WEKO 624340

Kurihara, Chieko

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栗原 千絵子

× 栗原 千絵子

WEKO 624341

en 栗原 千絵子

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抄録
内容記述タイプ Abstract
内容記述 Background;Selective serotonin reuptake inhibitors(SSRIs)including paroxetine have severe stimulant effect in their starting doses and at the time of dose escalation which is now called as activatioin syndrome. The main features of this phenomenon are abrupt uprising of agitaion and impulsivity, but activation syndrome by SSRIs resembling acutr phase of schizophrenia are rare.
Method;A case study of paroxetine induced hallucinatory-delusional state with non-systematic review of Literature. Results;A50years ofd male with first episode of moderate major depressive disorder(MDD)was subsided within 6weeks. He had no previous histrory of psychiatric disorders and had been in good social status with honest living until he got the sick leave by MDD.on returning work, his dosing of paroxeitine was uprisen to 30mg per day. After three days of dose escalation, he had auditory hallucination and persecutory delusion which resembled acute phase of schizophrenia, but had no sign of mania or hypomania as well as agitation or impulsivity. The hallucinatory-delusional state was gradually resolved with dose reduction of paroxetine. Literature search revealed activation syndrome with psychotic feature is rare. Conclusion;Discerning activation syndrome is clinically imprtant for this side effect impairs course of pathologic process. But those with psychotic feature could be easily misdiagnosed as acute onset schizophrenia if we have no idea of this phenomenon.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 The Kobe conference of the International Neuropsychiatic Association
発表年月日
日付 2009-09-13
日付タイプ Issued
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