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Functional Deficits in the Extrastriate Body Area in Schizophrenia
https://repo.qst.go.jp/records/62721
https://repo.qst.go.jp/records/62721dc201f8c-f3cc-40a2-8bac-80b0e0582212
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2008-09-17 | |||||
| タイトル | ||||||
| タイトル | Functional Deficits in the Extrastriate Body Area in Schizophrenia | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Takahashi, Hidehiko
× Takahashi, Hidehiko× 高橋 英彦 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose: Exercise and sports are increasingly being implemented in the management of schizophrenia. However, individuals living with schizophrenia generally show psychomotor poverty, incoordination and clumsiness, and have an impairment of motor skill learning, which have cution system. It is widely documented in psychological and neurocognitive studies that the systems that mediate action perception, imitation and execution overlap and interact with each other. Therefore, for understanding, learning and acquiring new skills, the process of action perception is as important as that of motor execution. Recent studies have suggested that body-selective extrastriate body area (EBA) in the posterior temporaloccipital cortex is involved not only in static visual perception of body parts but also in the planning, imagination and execution of actions. We aimed to investigate the EBA function in schizophrenia. Methods: Twelve schizophrenia patients (6 men and 6women) and 12 age-sex-matched control participants participated in the study. Using functional magnetic resonance imaging (fMRI) with a task designed to activate the EBA by goal-directed actions, we aimed to elucidate functional abnormality of the EBA during observation of goal-directed actions in patients with schizophrenia. Results: Compared to controls, the patients with schizophrenia demonstrated significantly less activation on the EBA during observation of sports-related goal-directed actions. Furthermore, the EBA activation in patients was negatively correlated with the severity of negative and general psychopathology symptoms measured by the Positive and Negative Syndrome Scale. Conclusions: Dysfunction of the EBA might reflect a difficulty in representing dynamic aspects of human actions and might lead to impairments of simulation, learning and execution of actions on schizophrenia. Furthermore, these impairments might lead to impairments of understanding actions of others, interpersonal communication, body awareness, and overall physical activity manifested as negative symptoms and general psychopathology symptoms. The results of this study seem to have some important clinical implications for the management of schizophrenia and merit further investigation of the role of sports in the rehabilitation for schizophrenia and their effects on EBA function. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 2nd WFSBP Asia-Pacific Congress and 30th Annual Meeting of JSBP | |||||
| 発表年月日 | ||||||
| 日付 | 2008-09-13 | |||||
| 日付タイプ | Issued | |||||
