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Carbon ion radiotherapy in NIRS
https://repo.qst.go.jp/records/62559
https://repo.qst.go.jp/records/625592b4f8b7d-a5f2-446f-8e6e-27a6029fda32
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2008-06-05 | |||||
| タイトル | ||||||
| タイトル | Carbon ion radiotherapy in NIRS | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Mizoe, Junetsu
× Mizoe, Junetsu× Tsujii, Hirohiko× 溝江 純悦× 辻井 博彦 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | High linear energy transfer (LET) charged particle therapy with carbon ions has been of interest in the treatment of malignant tumors because of better dose localization in the tumor volume and greater biologic effectiveness. In 1984, the Heavy Ion Medical Accelerator in Chiba (HIMAC) was constructed at the National Institute of Radiological Sciences (NIRS) as a part of the comprehensive 10-year strategy for cancer control in Japan. Between June 1994 and August 2007, a total of 3,452 patients were treated by carbon ion radiotherapy at NIRS. They consisted of 564 patients with prostate cancer, 488 patients with non small cell lung cancer, 432 patients with head and neck cancer (H&N), 374 patients with bone and soft tissue (B&S) sarcomas and so on. They also consisted of 1,561 patients of phase I/II dose escalation study and 1,891 patients of phase II clinical study. For the patients with prostate, H&N and B&S sarcomas, the results of phase II study with the dose fractionation methods of 16~20 fractions through 4~5 weeks showed good local control and acceptable late normal tissue morbidity. For the patients with hepatic cell carcinoma, phase II study by two fractions is ongoing. For the patients with NSCLC, phase I/II dose escalation study of one day fraction is undergoing. The results of phase II clinical studies and preliminary results of phase I/II studies showed acceptable normal tissue acute and late reactions and good local control of the irradiated sites. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 日独放射線医学交流計画第１４回ワークショップ | |||||
| 発表年月日 | ||||||
| 日付 | 2008-06-02 | |||||
| 日付タイプ | Issued | |||||
