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アイテム
Carbon Ion Radiotherapy for Eye Tumor
https://repo.qst.go.jp/records/62491
https://repo.qst.go.jp/records/6249151b181ec-4944-404a-a730-0214d9a7ccc8
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2008-03-26 | |||||
| タイトル | ||||||
| タイトル | Carbon Ion Radiotherapy for Eye Tumor | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Tsuji, Hiroshi
× Tsuji, Hiroshi× Kato, Hiroyuki× Yanagi, Takeshi× Kamada, Tadashi× Tsujii, Hirohiko× 辻 比呂志× 加藤 弘之× 柳 剛× 鎌田 正× 辻井 博彦 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose: To evaluate the applicability of carbon ion beams in the treatment of choroidal melanoma, with regard to normal tissue morbidity and local tumor control. Methods and Materials: Between January 2001 and August 2007, 78 patients with a locally advanced or of unfavorable site choroidal melanoma were enrolled to a phase I/II clinical trial of carbon-ion radiotherapy (C-ion RT) at the National Institute of Radiological Sciences (NIRS). Primary endpoint of this study was normal tissue morbidity and secondary endpoints were local tumor control and patient survival. Of those, 72 patients were followed up more than 6 months and analyzed. Results: Twenty-six patients (36%) have developed neovascular glaucoma and 3 of them received enucleation because of eye pain due to elevated intraocular pressure. Incidence of neovascular glaucoma was dependent on the tumor size and site. Eight patients died until the date of analysis, 6 died of distant metastasis of melanoma and 2 died of intercurrent diseases. One patient developed local recurrence of the treated tumor and two developed intraocular recurrence outside the irradiated area, the other 69 tumors were still controlled locally on the date of analysis. Seventeen patients developed distant metastasis, 12 in the liver, 4 in the lung, and 1 in the bone. 5 year overall survival, cause-specific survival, and intraocular control rates were 79.7%, 83.1%, and 91.4%, respectively. Conclusion: C-ion RT can be applied to choroidal melanoma with an acceptable morbidity and sufficient anti-tumor effect, even in the tumors of unfavorable size or site. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | NIRS-MD Anderson Symposium on Clinical Issues for Particle Therapy | |||||
| 発表年月日 | ||||||
| 日付 | 2008-03-22 | |||||
| 日付タイプ | Issued | |||||
