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The 13th International Congress of Radiation Research
https://repo.qst.go.jp/records/62163
https://repo.qst.go.jp/records/62163a5f190d1-18b4-4099-ba44-436cabdf652b
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-07-23 | |||||
| タイトル | ||||||
| タイトル | The 13th International Congress of Radiation Research | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Sakai, Kazuo
× Sakai, Kazuo× 酒井 一夫 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Combined effects of low dose/dose-rate irradiation and a carcinogenic agent A group of 5-week-old female C57BL/6N mice, 35 in each group, was irradiated with gamma-rays at 1.2, 0.65, or 0.35 mGy/hr for 35 days. The mice were then injected in the groin with 0.05 mg of 20-methylcholanthrene (MC) dissolved in olive oil and irradiation was continued. A statistically significant suppression of cumulative tumor incidences up to 200 days after MC injection was observed in the group irradiated at 1.2 mGy/hr. TD50 technique revealed that the ability for tumor rejection was increased in the irradiated mice. The incidence of thymic lymphoma induced by N-ethyl-N-nitrosourea (ENU) in B6C3F1 mice was synergistically increased by 4 weekly X-irradiation with 0.8 or 1.0 Gy given prior to the ENU administration. When the weekly dose was reduced to 0.2 or 0.4 Gy, on the other hand, the suppression of tumor incidence was observed. These results indicated that the low dose/dose-rate irradiation may suppress the process of chemical carcinogenesis, while larger doses resulted in its enhancement. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | The 13th International Congress of Radiation Research | |||||
| 発表年月日 | ||||||
| 日付 | 2007-07-15 | |||||
| 日付タイプ | Issued | |||||
