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Radiation Effects on Regulation of Gene Expression
https://repo.qst.go.jp/records/61867
https://repo.qst.go.jp/records/618673a8380a3-0bb6-470f-837b-b5fbddab7cc5
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2006-10-27 | |||||
| タイトル | ||||||
| タイトル | Radiation Effects on Regulation of Gene Expression | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Nenoi, Mitsuru
× Nenoi, Mitsuru× Bing, Wang× Nakajima, Tetsuo× 根井 充× 王 冰× 中島 徹夫 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Risk estimation of ionizing radiation in the middle to high dose range has been mainly based on the epidemiological studies on Hiroshima and Nagasaki A-Bomb survivors. However, the importance of molecular and cellular studies on mechanisms for the biological effects should be emphasized due to the inherent limitation of the epidemiological studies at low levels of radiation exposure and risk. An increasing number of low-dose ionization radiation-responsive genes are being repoted in mouse and human cells. Analyses of these genes are considered to provide clues to the mechanisms for low-dose radiation effects, because the major ionizing radiation-protection mechanisms, including cell cycle checkpoint regulation and apoptosis, involve the regulation of gene expression in response to ionizing radiation. Radioactive response is a biological response, by which individuals/cells acquire radiation-resistance after exposure to low-dose radiation. This is observed only after exposure to low-dose radiation, and is therefore considered to be an important determination of low-dose radiation risk. In this paper, authors describe the regulation of gene expression in low dose range. Especially, transcriptional regulation involved in the radioadaptive response will be discussed. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 20th CODATA International Conference | |||||
| 発表年月日 | ||||||
| 日付 | 2006-10-25 | |||||
| 日付タイプ | Issued | |||||
