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Analysis of organ movement during respiratory gated irradiation for particle radiotherapy

https://repo.qst.go.jp/records/59931
https://repo.qst.go.jp/records/59931
8208933c-4aa6-4dca-b551-738620dbc130
Item type 会議発表用資料 / Presentation(1)
公開日 2003-09-02
タイトル
タイトル Analysis of organ movement during respiratory gated irradiation for particle radiotherapy
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Minohara, Shinichi

× Minohara, Shinichi

WEKO 596121

Minohara, Shinichi

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Kanai, Tatsuaki

× Kanai, Tatsuaki

WEKO 596122

Kanai, Tatsuaki

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Endo, Masahiro

× Endo, Masahiro

WEKO 596123

Endo, Masahiro

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Katou, Hirotoshi

× Katou, Hirotoshi

WEKO 596124

Katou, Hirotoshi

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Miyamoto, Tadaaki

× Miyamoto, Tadaaki

WEKO 596125

Miyamoto, Tadaaki

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蓑原 伸一

× 蓑原 伸一

WEKO 596126

en 蓑原 伸一

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金井 達明

× 金井 達明

WEKO 596127

en 金井 達明

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遠藤 真広

× 遠藤 真広

WEKO 596128

en 遠藤 真広

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加藤 博敏

× 加藤 博敏

WEKO 596129

en 加藤 博敏

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宮本 忠昭

× 宮本 忠昭

WEKO 596130

en 宮本 忠昭

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抄録
内容記述タイプ Abstract
内容記述 Introduction: One of advantage in the use of heavy charged particles for radiotherapy is the high potential for concentrating a uniform prescribed dose to the target volume while minimizing irradiation to surrounding normal tissues. The compensator and collimator statically define a shape of the beam to conform the irradiation filed at each patient. However the target around thorax and abdomen moves physiologically in association with heartbeat, respiration and peristaltic function. These motions cause the decline in the dose concentration to the target volume. Prior discussions about organ motions have mainly focused on inferior-superior movement with respiration. In contrast, the anterior-posterior change of the target depth along the beam path is very important in particle radiotherapy, because the shape end of the beam (Bragg peak) is so sharp as to be matched to the distal edge of the target. In addition, depth variations for particle radiotherapy must be presented in water equivalent path length (WEL) using CT numbers. The purpose of this study is to analyze depth variations of organs from the aspect of respiratory-gated irradiation.
\nMethod: A set of sequential CT images was reconstructed from continuous X-ray projection data accumulated by dynamic scanning. At the same time of CT data acquisition, the respiratory signal of patient was measured. The timing of each CT image is related with the phase of respiration waveform. Then organ movements on these CT image are analyzed, and investigated the correlation with respiration waveform.
\nResults: In case of liver around diaphragm, the target depth along beam path was remarkably changed depending on the respiratory organ movement. The magnitude of depth variations was comparable to the inferior-superior movement. For example, changes in WEL from the iso-center to the body surfaces of the front and the back were 6.2 mm and 18.9 mm, respectively. These variations were estimated to reduce to less than 2 mm by gated irradiation.
In lung case, the correlation between the change in WEL of lung size and the respiratory signal appeared not to be clear. The change in WEL had two frequency components, one was respiration and other was heartbeat.
In pancreas case, the position of pancreas itself didn’t move so much. However air cavities in intestine along the beam path changed, and affected the target depth in WEL.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 World Congress on Medical Physics and Biomedical Engineering 2003
発表年月日
日付 2003-08-29
日付タイプ Issued
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