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Radiation-induced adaptive response with reference to evidence and significance: A review.
https://repo.qst.go.jp/records/57249
https://repo.qst.go.jp/records/572491b4b06f1-6fca-4ab8-a1d2-a151aec9c11e
| Item type | 一般雑誌記事 / Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-03-20 | |||||
| タイトル | ||||||
| タイトル | Radiation-induced adaptive response with reference to evidence and significance: A review. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Vares, Guillaume
× Vares, Guillaume× Bing, Wang× Tanaka, Kaoru× Nakajima, Tetsuo× Nenoi, Mitsuru× Hayata, Isamu× Ｇｕｉｌｌａｕｍｅ Ｖａｒｅｓ× 王 冰× 田中 薫× 中島 徹夫× 根井 充× 早田 勇 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In contradiction to classical paradigm, which assumes that radiation effects are directly proportional to energy deposit, numerous studies described the existence of a radiation-induced adaptive response, according to which pre-exposure to low priming dose of ionizing radiations decreases the biological effects of a subsequent higher challenging dose. Initially characterized in human lymphocytes, this phenomenon has since then been identified in a great variety of in vitro and in vivo models. Although few is known about molecular mechanisms implicated in radiation-induced adaptive response, DNA repair and p53-related pathways seem to play an important role. This mini-review addresses the current knowledge on in vitro, in vivo and in utero radioadaptive response, its characteristics and its consequences for carcinogenesis and risk assessment. Further research in this area of study may help to better understand bioresponse to low dose of radiation and build a new paradigm for evaluation of radiation risks. |
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| 書誌情報 |
Indian Journal of Radiation Research 巻 3, 号 1, p. 16-34, 発行日 2006 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0973-0168 | |||||
