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Effects of High Concentration Verteporfin and Ion Beams on the Expression of p53 in Human Cultured Retinal Endothelium
https://repo.qst.go.jp/records/56052
https://repo.qst.go.jp/records/560529303f75d-7af8-4cfa-b724-6408008b3b6f
| Item type | 一般雑誌記事 / Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-04-28 | |||||
| タイトル | ||||||
| タイトル | Effects of High Concentration Verteporfin and Ion Beams on the Expression of p53 in Human Cultured Retinal Endothelium | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
明尾, 潔 (あけお眼科医院)
× 明尾, 潔 (あけお眼科医院)× 舟山, 知夫× 小林, 泰彦× 明尾, 庸子 (あけお眼科医院)× 舟山 知夫× 小林 泰彦 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To examine how ion beams and verteporfin influence the expression of p53 in human cultured RE cells, the cells were incubated with verteporfin for 2 hrs and irradiated with Ne, C, and He ion beam. The result of quantitative PCR using LightCycler system showed that the high concentration verteporfin significantly decreased the expression of p53 in human RE cells up to 8 hrs after irradiation by He, and up to 24 hrs after irradiation by C, but none by Ne, suggesting the species of ion irradiation to influence the expression of p53 after addition of high concentration verteporfin to human RE cells in vitro. | |||||
| 書誌情報 |
QST Takasaki Annual Report 2015 p. 112-112, 発行日 2017-03 |
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| 出版者 | ||||||
| 出版者 | Takasaki Advanced Radiation Research Institute, QST | |||||
