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難治性消化器癌に対する重粒子線と上皮成長因子受容体 （EGFR) 阻害剤併用治療の基礎的検討
https://repo.qst.go.jp/records/55888
https://repo.qst.go.jp/records/55888cef4f603-b010-4d5c-87b4-7110befd2094
| Item type | 一般雑誌記事 / Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-11-18 | |||||
| タイトル | ||||||
| タイトル | 難治性消化器癌に対する重粒子線と上皮成長因子受容体 （EGFR) 阻害剤併用治療の基礎的検討 | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
篠藤, 誠
× 篠藤, 誠× 山田, 滋× 篠藤 誠× 山田 滋 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Aim of present study is to investigate the combination effect of carbon ion radiotherapy and epidermal growth factor receptor (EGFR) inhibitor for refractory gastrointestinal carcinoma in mice. We assessed the sensitization effect of gemcitabine and gefitinib (EGFR inhibitor) for carbon ion radiotherapy in tumor cells. Gefitinib (Iressa) has been reported to inhibit the proliferation of pancreatic cancer. And the degree of enhancement of radiation effect is increased with combining GEM and Iressa. In this study, we investigated the effectiveness of combining GEM and Iressa with carbon ion radiotherapy for pancreatic cancer. The addition of GEM and Iressa to carbon ion therapy was significantly decrease the tumor growth in compared to the carbonion alone. | |||||
| 書誌情報 |
放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書 号 HIMAC-136, p. 47-48, 発行日 2011-11 |
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| 出版者 | ||||||
| 出版者 | 放医研 | |||||
