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重粒子線治療における酸化ストレスおよび抗酸化力に関する研究
https://repo.qst.go.jp/records/55887
https://repo.qst.go.jp/records/55887bc8217ae-3a93-464c-96c9-b2c71ac97b4d
| Item type | 一般雑誌記事 / Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-11-18 | |||||
| タイトル | ||||||
| タイトル | 重粒子線治療における酸化ストレスおよび抗酸化力に関する研究 | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
山田, 滋
× 山田, 滋× 山田, 泰寿× 清水, 一範× 篠藤, 誠× 安藤, 興一× 山田 滋× 山田 泰寿× 清水 一範× 篠藤 誠× 安藤 興一 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Oxygen is required for respiration and the energetic processes that enable aerobic life. Free radical and reactive oxygen metabolite (ROM) formations create oxidative stress and contribute to various processes including aging, degenerative diseases and cancer. Additionally, they may have a role in the radiotherapy for various types of cancer. In this study, we aimed to investigate the degree of oxidative stress for carbon-ion radiotherapy in locally recurrent rectal cancer and pancreas cancer, and to find out whether the degree of oxidative stress shows any difference among different grade of normal tissue damages. It can be used as an index for their differential diagnosis. Sixteen patients with locally recurrent rectal cancer and 6 pancreas cancers were included in the study. The BAP levels were lower before carbon-ion treatment than after treatment. The ROM levels were significantly lower before treatment than after treatment. It might be possible to conclude that the serum BAP and ROM levels may be an index parameter for normal tissue damages. | |||||
| 書誌情報 |
放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書 号 HIMAC-136, p. 20-21, 発行日 2011-11 |
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| 出版者 | ||||||
| 出版者 | 放医研 | |||||
