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Regulation of Free Radical Generation in a Sample Irradiated by Heavy-Ion Beam – Density of Hydroxyl Radical -
https://repo.qst.go.jp/records/55769
https://repo.qst.go.jp/records/55769d1b0336f-c6f1-40b3-b3c8-4da337261d9d
| Item type | 一般雑誌記事 / Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2012-01-17 | |||||
| タイトル | ||||||
| タイトル | Regulation of Free Radical Generation in a Sample Irradiated by Heavy-Ion Beam – Density of Hydroxyl Radical - | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Matsumoto, Ken-ichiro
× Matsumoto, Ken-ichiro× Nakanishi, Ikuo× Anzai, Kazunori× 松本 謙一郎× 中西 郁夫× 安西 和紀 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Density of •OH in gelatin samples caused by irradiation of carbon ion beam was investigated. •OH was detected by EPR spin trapping technique using DMPO as a spin trapping agent. Gelatin samples containing several concentrations (7.7 to 1650 mM) of DMPO were irradiated by 290 MeV carbon mono beam using HIMAC, applying several LET (20 to 180 keV/micro-m) at the surface of the gelatin. The dose at the surface of the gelatin sample was 32 Gy. DMPO-OH (spin trapped •OH) in irradiated samples were detected by X-band EPR spectrometer. The experiments were repeated using X-ray. Amount of DMPO-OH generated by carbon-ion beam was markedly lower than that by X-ray. For carbon-ion beam, amount of DMPO-OH decreased with increasing LET. The EPR signal intensity of DMPO-OH in X-rayirradiated sample reached plateau around 30 mM DMPO; however, amount of DMPO-OH in carbon-beam-irradiated sample increased with concentration of DMPO added in the sample. This result suggests that •OH generation around the truck of carbon ion beam was much dense compared with X-ray. |
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| 書誌情報 |
Annual Report of the Research Project with Heavy Ions at NIRS-HIMAC 巻 NIRS-M-244, 号 HIMAC-136, p. 131-132, 発行日 2011-11 |
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| 出版者 | ||||||
| 出版者 | 放医研 | |||||
