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重粒子線治療の最適化のための生物学研究-VI；混合ビームの生物効果
https://repo.qst.go.jp/records/55409
https://repo.qst.go.jp/records/5540900a4bc3a-9ea0-46b1-b2cf-ed117daadc3b
| Item type | 一般雑誌記事 / Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2005-11-04 | |||||
| タイトル | ||||||
| タイトル | 重粒子線治療の最適化のための生物学研究-VI；混合ビームの生物効果 | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
古澤, 佳也
× 古澤, 佳也× 青木, 瑞穂× 平山, 亮一× 松本, 孔貴× 加瀬, 優紀× 松藤, 成弘× 金井, 達明× 古澤 佳也× 青木 瑞穂× 平山 亮一× 松本 孔貴× 加瀬 優紀× 松藤 成弘× 金井 達明 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To determine biological effectiveness of mixed LET heavy-ion particles, a rotating range shifter was designed, and measured the physical characteristics. The shifter made from 4 mm thick brass blade having different duty cycle produced a dual-peak Bragg curve (DBP: dual Bragg-peak). The range of the 2nd peak was shifted to up stream 21.4 mm as water equivalent depth from the original peak. From 135 MeV/u carbon beam or 500 MeV/u iron beams with adequate binary filter, we could obtain (estimated) 190 and 27.8 keV/um or 1000 and 300 keV/um DBP beams that calculated from the residual range of each peak. Chinese hamster V79 cells were irradiated at the position with the rotating range shifter, fixed blade, or without any shifters. The survival curve with the rotating range shifter showed higher radiobiological effect compared with an expected response for carbon beam, but lower effects for iron beams, that calculated from the survival curves with fixed blade and without shifters under an assumption | |||||
| 書誌情報 |
放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書 巻 2005, p. 46-47, 発行日 2005-05 |
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| 出版者 | ||||||
| 出版者 | 放医研 | |||||
