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  1. 研究・技術・調査報告

Influence of the shielding on the space radiation biological effectiveness

https://repo.qst.go.jp/records/55246
https://repo.qst.go.jp/records/55246
b67ee680-a4c1-4bff-99af-5056bbed5b31
Item type 一般雑誌記事 / Article(1)
公開日 2004-01-25
タイトル
タイトル Influence of the shielding on the space radiation biological effectiveness
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Matsumoto, Hideki

× Matsumoto, Hideki

WEKO 565087

Matsumoto, Hideki

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Hayashi, Saxhiko

× Hayashi, Saxhiko

WEKO 565088

Hayashi, Saxhiko

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Hui, Jin Zhao

× Hui, Jin Zhao

WEKO 565089

Hui, Jin Zhao

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Hatashita, Masanori

× Hatashita, Masanori

WEKO 565090

Hatashita, Masanori

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Kano, Eiichi

× Kano, Eiichi

WEKO 565091

Kano, Eiichi

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Oonishi, Takeo

× Oonishi, Takeo

WEKO 565092

Oonishi, Takeo

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Furusawa, Yoshiya

× Furusawa, Yoshiya

WEKO 565093

Furusawa, Yoshiya

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松本 英樹

× 松本 英樹

WEKO 565094

en 松本 英樹

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大西 武雄

× 大西 武雄

WEKO 565095

en 大西 武雄

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古澤 佳也

× 古澤 佳也

WEKO 565096

en 古澤 佳也

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抄録
内容記述タイプ Abstract
内容記述 To investigate whether the bystander effect mediated nitric oxide (NO) radicals excreted from the tumor irradiated with accelerated carbon ion beams modulates growth of the unirradiated tumor at an opposite side in the same mouse. Also, to investigate whether NO generating agents can sensitize the tumoricidal effect by accelerated carbon ion beams.
NO at the relatively low concentrations, which excreted from the irradiated donor tumors with accelerated carbon ion beams induced both inhibition and stimulation of tumor regrowth. These findings indicate the importance of an intercellular signal transduction pathway initiated by NO in cellular response to radiation. On the other hand, NO at the relatively high concentrations (0.3 mM) sensitized the tumoricidal effect of X-rays in the p53-independent manner.
書誌情報 Annual Report of the Research Project with Heavy Ions at NIRS-HIMAC

巻 2002, p. 155-156, 発行日 2003-04
出版者
出版者 放医研
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