ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

  1. 研究・技術・調査報告

太陽紫外線による細胞のアポトーシスとサンスクリーンの効果

https://repo.qst.go.jp/records/55004
https://repo.qst.go.jp/records/55004
13379734-3653-42cd-be74-d49a98e17ec8
Item type 一般雑誌記事 / Article(1)
公開日 2002-06-14
タイトル
タイトル 太陽紫外線による細胞のアポトーシスとサンスクリーンの効果
言語
言語 jpn
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 古澤, 佳也

× 古澤, 佳也

WEKO 562651

古澤, 佳也

Search repository
青木, 瑞穂

× 青木, 瑞穂

WEKO 562652

青木, 瑞穂

Search repository
古澤 佳也

× 古澤 佳也

WEKO 562653

en 古澤 佳也

Search repository
青木 瑞穂

× 青木 瑞穂

WEKO 562654

en 青木 瑞穂

Search repository
抄録
内容記述タイプ Abstract
内容記述 An outbreak of skin cancer may be caused by exposure of ultraviolet light in the sunlight through induction of apoptosis on skin cells. Shielding the skin from the sunlight, especially from the UV-B light by use of sunscreen is thought to be important to escape the harmfulness. However, action spectrum for the induction of apoptosis by the ultraviolet light is not well known. To determine the action spectrum of apoptosis upon mammalian cells, L5178Y cells were used, and the wavelength dependence of the apoptosis exposed to ultraviolet light was investigated using monochromatic lights from the Okazaki Large Spectrograph (OLS) at the National Institute of Basic Biology (INBB), Okazaki, quasi monochromatic light from filtrated lights by mercury lamps or fluorescent lamps, and from natural sunlight. Cells were exposed to ultraviolet light at different wavelengths in the UV-A, -B, and -C regions, and the frequencies of apoptotic cells in total cells were determined with chromatin condensation after fluorescent staining following adequate post-incubation after UV exposure. The light-exposure level used to induce apoptosis in 10% of the cells were 24 J/m2, 182 J/m2, and 141 kJ/m2 at 280, 300, and 320 nm, respectively. The measured action spectrum for apoptosis induction showed a slightly steeper curve to that for the minimum erythema dose (MED). The peak of the effective action spectrum for induction of apoptosis to sunlight i.e. the products of spectra for apoptosis induction or MED and solar-light intensity on the ground, was found at 303 nm, which was also took place in shorter wavelengths region than that for MED. The difference between the effective action spectrum may be caused by the shielding of the skin keratinocytes locating just above the target cells.
書誌情報 コスメトロジー研究報告

巻 9, p. 2-9, 発行日 2001-09
戻る
0
views
See details
Views

Versions

Ver.1 2023-05-15 22:54:31.758011
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR 2.0
  • OAI-PMH JPCOAR 1.0
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3