WEKO3
アイテム
EPR Based Estimation of Radiation-Induced Reactive Oxygen Species
https://repo.qst.go.jp/records/54791
https://repo.qst.go.jp/records/54791fcdf9e68-7ef4-4a7f-83d9-c32c1b43116e
| Item type | 会議発表論文 / Conference Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-07-12 | |||||
| タイトル | ||||||
| タイトル | EPR Based Estimation of Radiation-Induced Reactive Oxygen Species | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
| 資源タイプ | conference paper | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Matsumoto, Kenichiro
× Matsumoto, Kenichiro× Ueno, Megumi× Nyui, Minako× Ogawa, Yukihiro× Kamibayashi, Masato× Sekine, Emiko× Nakanishi, Ikuo× Anzai, Kazunori× Ozawa, Toshihiko× 松本 謙一郎× 上野 恵美× 乳井 美奈子× 小川 幸大× 上林 將人× 関根 絵美子× 中西 郁夫× 安西 和紀× 小澤 俊彦 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Generation of reactive oxygen species (ROS) is considered as essential trigger of biological effects of ionizing radiations, and may be deeply linked with the radiation quality. \nAmounts of total oxidation reactions (i.e. oxidative free radical species, ●OH and HO2●–), H2O2 generations, Oxygen consumptions, and •OH generations induced by X-ray, 20 keV/μm carbon beam, and 80 keV/μm carbon beam were estimated using EPR based techniques. \nTotal oxidation reactions were estimated as 3, 1.3, and 0.66 μmol/L/Gy, amount of H2O2 generations were 0.2, 0.57, and 0.35 μmol/L/Gy, oxygen consumptions were 0.4, 0.39, and 0.15 μmol/L/Gy for X-ray, 20 keV/μm carbon beam, and 80 keV/μm carbon beam, respectively. The ratio of H2O2 generation per oxygen consumption were increased with LET, and were 0.5, 1.46, 2.33 for X-ray, 20 keV/μm carbon beam, and 80 keV/μm carbon beam, respectively. The ●OH generations expected to be localized on the track/range of the radiation beam/ray, and both sparse (≈ 3.3 mM) and very dense (> 1.7 M) ●OH generations were suggested. Percentage of sparse ●OH generation decreased with LET becoming higher. |
|||||
| 書誌情報 |
Free Radical Biology and Medicine 巻 100, 号 Supplement, p. S27-S27, 発行日 2016-11 |
|||||
| 出版者 | ||||||
| 出版者 | Elsevier | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.freeradbiomed.2016.10.066 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.sciencedirect.com/science/article/pii/S0891584916305378 | |||||
| 関連名称 | http://www.sciencedirect.com/science/article/pii/S0891584916305378 | |||||
