WEKO3
アイテム
Verification of Two Different Hydroxyl Radical Densities in Aqueous Solution by Radiation
https://repo.qst.go.jp/records/54788
https://repo.qst.go.jp/records/547886ad4fa8a-d395-4952-a783-19a82ce19672
| Item type | 会議発表論文 / Conference Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-07-12 | |||||
| タイトル | ||||||
| タイトル | Verification of Two Different Hydroxyl Radical Densities in Aqueous Solution by Radiation | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
| 資源タイプ | conference paper | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Ogawa, Yukihiro
× Ogawa, Yukihiro× Sekine, Emiko× Matsumoto, Kenichiro× 小川 幸大× 関根 絵美子× 松本 謙一郎 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Hydroxyl radical (●OH) is recognized a key player in biological effects of radiation. In this study, X-ray or heavy-ion beam induced ●OH generation was evaluated using fluorescent probe method. The eccentrically-located ●OH generations and the super-localized ●OH generations, which were previously reported based on EPR spin-trapping method, were again confirmed with a different types of analysis. Several concentrations (0.5-208 mM) of terephthalic acid disodium (TPA-Na) in aqueous solution were irradiated with 32 Gy X-ray or a heavy-ion beam (C400, Si490 or Fe500). The amount of ●OH adduct of TPA-Na (hydroxyl terephthalate: hTPA) generated was measured by fluorophotometer (Ex.310 nm/Em. 425 nm). The relationship between the molecular density of TPA-Na in the reaction mixture and hTPA generated was analyzed. The amount of hTPA was increased in proportion to the molecular density of TPA-Na and reached plateau. The inflexion point was not changed by type of ray. The inflexion point suggests the relatively a concentration of ●OH generation. In the case of heavy-ion beam, another linear trend that passed through the origin was again observed when TPA-Na density was extremely high. This second linear increasing of hTPA suggested extremely "dense" generation of ●OH. | |||||
| 書誌情報 |
Free Radical Biology and Medicine 巻 100, 号 Supplement, p. S28-S28, 発行日 2016-11 |
|||||
| 出版者 | ||||||
| 出版者 | Elsevier | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.freeradbiomed.2016.10.069 | |||||
