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Carbon-ion Radiotherapy for Hepatocellular Carcinoma
https://repo.qst.go.jp/records/54428
https://repo.qst.go.jp/records/5442853990b70-823d-460e-b3bd-6331e034dc99
| Item type | 会議発表論文 / Conference Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-12-12 | |||||
| タイトル | ||||||
| タイトル | Carbon-ion Radiotherapy for Hepatocellular Carcinoma | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
| 資源タイプ | conference paper | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Yasuda, Shigeo
× Yasuda, Shigeo× Harada, Mayumi× Yamada, Shigeru× Shiomi, Miho× Isozaki, Teturou× Kamada, Tadashi× 安田 茂雄× 原田 麻由美× 山田 滋× 塩見 美帆× 磯崎 哲朗× 鎌田 正 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Abstract Clinical trials of carbon ion radiotherapy (C-ion RT) for hepatocellular carcinoma (HCC) were conducted at the National Institute of Radiological Sciences (NIRS) in Japan between April 1995 and August 2005. In four clinical studies, we tried to determine the optimal dose and to shorten the treatment duration using five different fractionation schedules comprising 15, 12, eight, four and two fractions. There have been no treatment-related deaths and no severe adverse events. As a result of these studies, the duration of treatment could be reduced from five weeks to two days. Two-fraction therapy is currently ongoing, licensed as a Highly Advanced Medical Technology. Between April 2003 and August 2012, 133 patients with HCC underwent two fraction C-ion RT. There were no cases of grade 4 toxicity. The local control rates were 98% and 83% at one and three years, respectively, with a total dose of 45.0 GyE. Because of the low toxicity and good local control rate, C-ion RT is a promising radical and minimally invasive therapeutic option for HCC. |
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| 書誌情報 |
NIRS＆MedAustron Joint Symposium on Carbon Ion Radiotherapy p. 38-46, 発行日 2013-12 |
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