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Reduction in Malformations by Low Dose Pre-Irradiation: The Early Beginning of Adaptive Response Story in Fetal Mice
https://repo.qst.go.jp/records/54038
https://repo.qst.go.jp/records/54038c5c25aba-56ad-41c2-b829-ffc15ea68568
Item type | 会議発表論文 / Conference Paper(1) | |||||
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公開日 | 2008-10-06 | |||||
タイトル | ||||||
タイトル | Reduction in Malformations by Low Dose Pre-Irradiation: The Early Beginning of Adaptive Response Story in Fetal Mice | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
資源タイプ | conference paper | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Bing, Wang
× Bing, Wang× Tanaka, Kaoru× Shang, Yi× Nakajima, Tetsuo× Nenoi, Mitsuru× Hayata, Isamu× 王 冰× 田中 薫× 尚 奕× 中島 徹夫× 根井 充× 早田 勇 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Radiation-induced adaptive response is defined as the phenomenon of priming low-dose-induced resistance to subsequent irradiation at higher doses. Research on adaptive response, which provides important scientific basis for radiation risk estimates and offer significant insight into the defense mechanisms regarding radiation protection, is of great concern for both public health and academic research. In the in-vitro examinations, diminished detrimental effects such as chromosome aberrations, mutations, transformation and cell death are documented. In the in vivo investigations, adaptive response is recorded mainly as a rescuing effect resulting in an improved survival. In a series of studies using an in utero model with fetal mice, we demonstrated the existence of adaptive response and characterized the experimental conditions for its successful induction | |||||
書誌情報 |
Proceedings of NIRS International Symposium on the Effects of Low Dose Radiation 巻 NIRS-M-211, p. 16-22, 発行日 2008-03 |
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出版者 | ||||||
出版者 | National Institute of Radiological Sciences | |||||
ISBN | ||||||
識別子タイプ | ISBN | |||||
関連識別子 | 978-4-9389-8751 |