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Effective Biomarkers for Proof-of-Concept
https://repo.qst.go.jp/records/53930
https://repo.qst.go.jp/records/53930054f5814-8530-4b49-a208-b0326b5bbe02
| Item type | 会議発表論文 / Conference Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2008-03-12 | |||||
| タイトル | ||||||
| タイトル | Effective Biomarkers for Proof-of-Concept | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
| 資源タイプ | conference paper | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Suhara, Tetsuya
× Suhara, Tetsuya× Kodaka, Fumitoshi× 須原 哲也× 小高 文聰 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Effective biomarkers have been needed for diagnostic purpose and evaluation of the effects of drugs.Positron emission tomography(PET)enables us to viualize several components of brain activites including glucise metabolism of brain activity and neurotransmitter receptors and transporters.In vivo neuroimaging including neuroreceptor imaging and enzyme activity imaging have contributed to drug evaluation by1)ratinal drug dosing,2)biodistribution of drug,3)therapeutic rationale for drug utilization,and4)mechanism of drug action[1].In this article,we focused on rational drug dosing using receptor occupancy and proof-of-concept of drugs,as well as new therapeutic methods using PET. | |||||
| 書誌情報 |
Current Medical Imaging Reviews 巻 4, p. 25-27, 発行日 2008-04 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1573-4056 | |||||
