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培養がん細胞における重粒子線照射の利点
https://repo.qst.go.jp/records/53369
https://repo.qst.go.jp/records/53369a5b0573e-3a11-4c9e-b81d-1b5bff756f5d
| Item type | 会議発表論文 / Conference Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2004-08-26 | |||||
| タイトル | ||||||
| タイトル | 培養がん細胞における重粒子線照射の利点 | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
| 資源タイプ | conference paper | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
古澤, 佳也
× 古澤, 佳也× 古澤 佳也 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Accelerated heavy-ion beams has unique characteristics from the radiobiological point of view. This characteristic makes advantages and difficulties on heavy-ion radiotherapy, also makes difficult to understand the response of irradiated cells. Linear energy transfer (LET) of heavy-ion beams changes with depth in materials, and this change modifies the relative radiobiological effectiveness (RBE). Radiobiological effects were higher for lighter ion-beams at the same LET. The RBE increased with the increase of LET, showed a peak at around 100-200 keV/um, then decreased with farther increase of LET. These LET-RBE spectra shifted to higher LET region, the maximum RBE values decreased, and width of the peak of the RBE increased with increase of atomic number of accelerated ions. The peak of the RBE was only found in DNA-double strand break repair cells, but not in repair deficient cell strains. | |||||
| 書誌情報 |
テーラーメイド放射線治療を目指して : 第2回重粒子医科学センター・第1回フロンティア研究センター合同シンポジウム p. 85-90, 発行日 2003-06 |
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| 出版者 | ||||||
| 出版者 | 実業公報社 | |||||
