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XANES spectral changes of hydrated deoxyribose induced by K-shell ionization of oxygen
https://repo.qst.go.jp/records/49599
https://repo.qst.go.jp/records/49599d5b7c498-2e24-45d9-bb53-07f48c644e40
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-02-12 | |||||
| タイトル | ||||||
| タイトル | XANES spectral changes of hydrated deoxyribose induced by K-shell ionization of oxygen | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
藤井, 健太郎
× 藤井, 健太郎× 横谷, 明徳× 藤井 健太郎× 横谷 明徳 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We investigated the initial process of DNA strand breakage induced by ionizing radiation by recording XANES spectra of hydrated deoxyribose (dR) films before and after K-shell ionization of oxygen. The experiments were performed on beamline BL23SU at SPring-8, Japan. The hydrated dR films were prepared by exposing the cooled dR film surface to water vapor. The XANES spectra were then obtained by measuring the sample drain current. The soft X-ray irradiation treatment led to an increase in the intensity of the s*(C=O) peak (around 532 eV) and a decrease in the intensity of the s*(C–O) peak around 538 eV). Furthermore, a characteristic peak was observed at around 534–536 eV in the hydrated dR film after irradiation. This peak, which was ascribed to a newly formed carboxyl group, was not observed in the XANES spectrum of the dry dR film after irradiation. This carboxyl group was considered to originate from the reaction of a nearby water molecule with the carbonyl group produced by the direct ionization of dR. This structure may be formed at the strand-break termini of DNA after radiation damage. Therefore, waters of hydration may play a protective role against irreparable strand breakage. |
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| 書誌情報 |
AIP Conference Proceedings 巻 2054, p. 040005, 発行日 2019-01 |
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| 出版者 | ||||||
| 出版者 | American Institute of Physics | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1063/1.5084606 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://aip.scitation.org/doi/pdf/10.1063/1.5084606 | |||||
| 関連名称 | https://aip.scitation.org/doi/pdf/10.1063/1.5084606 | |||||
