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Deletion of TLS polymerases promotes homologous recombination in Arabidopsis
https://repo.qst.go.jp/records/49520
https://repo.qst.go.jp/records/49520ae45caff-75df-424b-902a-91b28ef0dfc3
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-01-29 | |||||
| タイトル | ||||||
| タイトル | Deletion of TLS polymerases promotes homologous recombination in Arabidopsis | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
坂本, 綾子
× 坂本, 綾子× Kaya, Hidetaka× Endo, Masaki× 坂本 綾子 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To investigate how TLS activities are regulated and how the stalled replication fork is processed in plants, reversion frequencies and homologous recombination (HR) frequencies were analyzed using GUS-based substrates. The HR frequencies in plants deficient in DNA polymerase ζ or Rev1 were higher than that in wildtype plants under normal conditions. To examine the role of HSP90 in the regulation of damage tolerance, we analyzed reversion frequencies and HR frequencies in plants grown in the presence of a HSP inhibitor, GDA. Reversion frequency was lower in GDA-treated plants than controls. The HR frequency was higher in GDA-treated wildtype plants than controls. These results suggest that HSP90 interacts with TLS polymerase(s), which promotes error-prone TLS in plants. | |||||
| 書誌情報 |
Plant Signaling & Behavior 巻 13, 号 7, 発行日 2018-06 |
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| 出版者 | ||||||
| 出版者 | Taylor & Francis Online | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 29944437 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1080/15592324.2018.1483673 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.tandfonline.com/toc/kpsb20/current | |||||
| 関連名称 | https://www.tandfonline.com/toc/kpsb20/current | |||||
