WEKO3
アイテム
A 3-dimensional hemispherical brain phantom for compact dedicated brain PET scanners
https://repo.qst.go.jp/records/49453
https://repo.qst.go.jp/records/4945369a7aa54-ae78-455c-99da-ab562b2ed7a6
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-01-15 | |||||
| タイトル | ||||||
| タイトル | A 3-dimensional hemispherical brain phantom for compact dedicated brain PET scanners | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Akamatsu, Go
× Akamatsu, Go× Tashima, Hideaki× Iwao, Yuma× Wakizaka, Hidekatsu× Maeda, Takamasa× Yoshida, Eiji× Yamaya, Taiga× Akamatsu, Go× Tashima, Hideaki× Iwao, Yuma× Wakizaka, Hidekatsu× Maeda, Takamasa× Yoshida, Eiji× Yamaya, Taiga |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Anew brain-dedicated compact PET scanner with hemispherical detector arrangement has been recently proposed for high-sensitivity brain imaging. An appropriate standard phantom is highly required for an objective performance evaluation. The Hoffman 3-dimensional (3D) brain phantom has been widely used as a de-facto standard brain phantom. However, the Hoffman phantom cannot be inserted into hemispherical PET scanners because the phantom has a cylindrical shape outside, which is different from the actual human head. Therefore, the purpose of this study is to develop a 3D ‘hemispherical’ brain phantom which is applicable to various scanners including the scanners with hemispherical detector arrangement. Changing outer shell into a hemispherical shape while maintaining the same radioactivity distribution as the original Hoffman phantom was the key. We performed a simulation study and an actual PET/CTstudy comparing the original Hoffman and hemispherical phantoms. In the simulation, we evaluated the count characteristics, image noise and voxel-by-voxel differences between phantom images and the digital reference. In the actual PET/CT study, we compared the PET images of the two phantoms using a commercial PET/CT scanner. As a result, in the simulation study, the noise equivalent count rate of the hemispherical phantom was higher than that of the original Hoffman phantom by about 20%. Onthe other hand, the difference in the image noise was not considerable and average global absolute voxel-by-voxel differences from the reference were almost same between the cylindrical and hemispherical phantoms. In the actual PET/CT study, the hemispherical phantom was validated to use imaging performance evaluation, and the obtained percent contrast was comparable with the original Hoffman phantom. The developed hemispherical phantom is useful for compact PET scanners with hemispherical detector arrangement in view of evaluation of appropriate scanning/reconstruction parameters and validation of the imaging performance towards clinical and widespread applications. |
|||||
| 書誌情報 |
Biomedical Physics & Engineering Express 巻 5, 号 2, p. 025013, 発行日 2019-02 |
|||||
| 出版者 | ||||||
| 出版者 | IOP publishing | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 2057-1976 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1088/2057-1976/aaf77f | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://iopscience.iop.org/article/10.1088/2057-1976/aaf77f | |||||
