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A computational model of internal representations of chemical gradients in environments for chemotaxis of Caenorhabditis elegans
https://repo.qst.go.jp/records/49436
https://repo.qst.go.jp/records/49436612a2903-461a-4fbc-94d5-99b9d90f9a94
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-01-09 | |||||
| タイトル | ||||||
| タイトル | A computational model of internal representations of chemical gradients in environments for chemotaxis of Caenorhabditis elegans | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Soh, (Hiroshima Univ.) Zu
× Soh, (Hiroshima Univ.) Zu× Sakamoto, (Hiroshima Univ.) Kazuma× Suzuki, Michiyo× Iino, (The Univ. of Tokyo) Yuichi× Tsuji, (Hiroshima Univ.) Toshio× 鈴木 芳代 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The small roundworm Caenorhabditis elegans employs two strategies, termed pirouette and weathervane, which are closely related to the internal representation of chemical gradients parallel and perpendicular to the travelling direction, respectively, to perform chemotaxis. These gradients must be calculated from the chemical information obtained at a single point, because the sensory neurons are located close to each other at the nose tip. To formulate the relationship between this sensory input and internal representations of the chemical gradient, this study proposes a simple computational model derived from the directional decomposition of the chemical concentration at the nose tip that can generate internal representations of the chemical gradient. The ability of the computational model was verified by using a chemotaxis simulator that can simulate the body motions of pirouette and weathervane, which confirmed that the computational model enables the conversion of the sensory input and head-bending angles into both types of gradients with high correlations of approximately r > 0.90 (p < 0.01) with the true gradients. In addition, the chemotaxis index of the model was 0.64, which is slightly higher than that in the actual animal (0.57). In addition, simulation using a connectome-based neural network model confirmed that the proposed computational model is implementable in the actual network structure. | |||||
| 書誌情報 |
Scientific Reports 巻 8, p. 17190, 発行日 2018-11 |
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| 出版者 | ||||||
| 出版者 | Springer Nature Limited. | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 2045-2322 (online) | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1038/s41598-018-35157-1 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.nature.com/articles/s41598-018-35157-1 | |||||
| 関連名称 | https://www.nature.com/articles/s41598-018-35157-1 | |||||
