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  1. 原著論文

A prediction model of working memory across health and psychiatric disease using whole-brain functional connectivity.

https://repo.qst.go.jp/records/49355
https://repo.qst.go.jp/records/49355
43f34e34-a50f-4379-9eab-697b051a81b5
Item type 学術雑誌論文 / Journal Article(1)
公開日 2018-12-25
タイトル
タイトル A prediction model of working memory across health and psychiatric disease using whole-brain functional connectivity.
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Yamashita, Masahiro

× Yamashita, Masahiro

WEKO 748914

Yamashita, Masahiro

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Yoshihara, Yujiro

× Yoshihara, Yujiro

WEKO 748915

Yoshihara, Yujiro

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Hashimoto, Ryuichiro

× Hashimoto, Ryuichiro

WEKO 748916

Hashimoto, Ryuichiro

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Yahata, Noriaki

× Yahata, Noriaki

WEKO 748917

Yahata, Noriaki

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Ichikawa, Naho

× Ichikawa, Naho

WEKO 748918

Ichikawa, Naho

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Sakai, Yuki

× Sakai, Yuki

WEKO 748919

Sakai, Yuki

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Yamada, Takashi

× Yamada, Takashi

WEKO 748920

Yamada, Takashi

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Matsukawa, Noriko

× Matsukawa, Noriko

WEKO 748921

Matsukawa, Noriko

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Okada, Go

× Okada, Go

WEKO 748922

Okada, Go

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C Tanaka, Saori

× C Tanaka, Saori

WEKO 748923

C Tanaka, Saori

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Kasai, Kiyoto

× Kasai, Kiyoto

WEKO 748924

Kasai, Kiyoto

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Kato, Nobumasa

× Kato, Nobumasa

WEKO 748925

Kato, Nobumasa

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Okamoto, Yasumasma

× Okamoto, Yasumasma

WEKO 748926

Okamoto, Yasumasma

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Seymour, Ben

× Seymour, Ben

WEKO 748927

Seymour, Ben

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Takahashi, Hidehiko

× Takahashi, Hidehiko

WEKO 748928

Takahashi, Hidehiko

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Kawato, Mitsuo

× Kawato, Mitsuo

WEKO 748929

Kawato, Mitsuo

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Imamizu, Hiroshi

× Imamizu, Hiroshi

WEKO 748930

Imamizu, Hiroshi

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Yahata, Noriaki

× Yahata, Noriaki

WEKO 748931

en Yahata, Noriaki

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抄録
内容記述タイプ Abstract
内容記述 Working memory deficits are present in many neuropsychiatric diseases with diagnosis-related severity. However, it is unknown whether this common behavioral abnormality is a continuum explained by a neural mechanism shared across diseases or a set of discrete dysfunctions. Here, we performed predictive modeling to examine working memory ability (WMA) as a function of normative whole-brain connectivity across psychiatric diseases. We built a quantitative model for letter 3-back task performance in healthy participants, using resting state functional magnetic resonance imaging (rs-fMRI). This normative model was applied to independent participants ( = 965) including four psychiatric diagnoses. Individual's predicted WMA significantly correlated with a measured WMA in both healthy population and schizophrenia. Our predicted effect size estimates on WMA impairment were comparable to previous meta-analysis results. These results suggest a general association between brain connectivity and working memory ability applicable commonly to health and psychiatric diseases.
書誌情報 eLife

巻 7, 発行日 2018-12
出版者
出版者 eLife Sciences Publications, Ltd
ISSN
収録物識別子タイプ ISSN
収録物識別子 2050-084X
PubMed番号
識別子タイプ PMID
関連識別子 30526859
DOI
識別子タイプ DOI
関連識別子 10.7554/eLife.38844
関連サイト
識別子タイプ URI
関連識別子 https://elifesciences.org/articles/38844
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