WEKO3
アイテム
Novel analytical study for reaction intermediates in the primary radiation interaction of DNA using a synchrotron radiation induced luminescence spectroscopy
https://repo.qst.go.jp/records/49188
https://repo.qst.go.jp/records/491882af1a74d-a2c3-4671-b2d8-fd5bf4b1aff0
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-10-01 | |||||
| タイトル | ||||||
| タイトル | Novel analytical study for reaction intermediates in the primary radiation interaction of DNA using a synchrotron radiation induced luminescence spectroscopy | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kojima, T.
× Kojima, T.× H.Aihara× Y.Kodashima× Makishima, H.× Nakiri, S.× Takeda, S.× Shimada, H.× Ukai, M.× .Ozga, C× Holzapfel, X.× Schimidt, Ph.× C., Küstner-Wetekamm× Otto, H.× Knie, A.× Ehresmann, A.× 横谷, 明徳× 藤井, 健太郎× Fukuda, Y.× Yokoya, Akinari× Fujii, Kentaro |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To identify the precise molecular processes to induce DNA lesions, we attempt a novel spectroscopy of luminescence excitation (LEX) induced by soft X-ray synchrotron radiation, which is a non-destructive analysis of the reaction intermediates in the elementary reaction pathway of damage induction and self-organized restoration. Using a liquid micro-jet technique to introduce aqueous samples in a vacuum chamber, we measure UV-visible luminescence from nucleotide solution as a function of the soft X-ray energy from nitrogen to oxygen K-edge region. The LEX intensities for the nucleotide solutions are significantly enhanced in the soft X-ray region (410-530 eV) which is ascribed to the K-shell excitation/ionization of nitrogen atoms in the nucleobases. Furthermore, the LEX spectra do not show any signature of X-ray absorption near-edge structure (XANES) of the nucleobases. This is because the luminescence intensities collected from the integral area of micro-jet only reflect a quantum yield of luminescence of the absorbed X-ray into UV-visible light irrespective of the absorption cross sections, i.e., of XANES. Thus the present result is the first evidence of luminescence as a result of X-ray absorption of aqueous nucleotides. | |||||
| 書誌情報 |
Radiation Protection Dosimetry 巻 183, p. 32-35, 発行日 2019-02 |
|||||
| 出版者 | ||||||
| 出版者 | Oxford University Press | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1742-3406 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1093/rpd/ncy239 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://academic.oup.com/rpd/article/183/1-2/32/5315817 | |||||
