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Localized hydroxyl radical generation at mmol/l and mol/l levels in water by photon irradiation
https://repo.qst.go.jp/records/49169
https://repo.qst.go.jp/records/491692494221a-7f55-4cfb-8da8-6a1aae4c36a7
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-01-18 | |||||
| タイトル | ||||||
| タイトル | Localized hydroxyl radical generation at mmol/l and mol/l levels in water by photon irradiation | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Ogawa, Yukihiro
× Ogawa, Yukihiro× Emiko, Sekine-Suzuki× Ueno, Megumi× Nakanishi, Ikuo× Ken-ichiro, Matsumoto× Yukihiro, Ogawa× Emiko, Sekine× Megumi, Ueno× Ikuo, Nakanishi× Kenichiro, Matsumoto |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The generation of localized hydroxyl radical (•OH) in aqueous samples by low linear energy transfer (LET) irradiation was investigated. Several concentrations of 5,5-dimethyl-1-pyrroline-N-oxid (DMPO) solution (from 0.5 to 1680 mmol/l) were prepared and irradiated with an identical dose of X-ray or γ-ray. The density of •OH generation in aqueous solution was evaluated by the electron paramagnetic resonance (EPR) spin-trapping technique using DMPO as an EPR spin-trapping agent. The relationship between the molecular density of DMPO in the samples and the concentration of DMPO-OH generated in the irradiated samples was analyzed. Two different characteristic linear trends were observed in the DMPO-OH/DMPO plots, which suggested •OH generation in two fashions, i.e., mmol/l- and mol/l-level local concentrations. The dose, dose rate, and/or the energy of photon irradiation did not affect the shapes of the DMPO-OH/DMPO plots. Moreover, the addition of 5 mmol/l caffeine could cancel the contribution of mmol/l-level •OH generation, leaving a trace of mol/l-level •OH generation. Thus, the localized mmol/l- and mol/l-level generations of •OH, which were independent of experimental parameters such as dose, dose rate, and/or the energy of photon of low LET radiation, were established. | |||||
| 書誌情報 |
Journal of Clinical Biochemistry and Nutrition 巻 63, 号 2, p. 97-101, 発行日 2018-05 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0912-0009 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 30279619 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.3164/jcbn.18-15 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.jstage.jst.go.jp/article/jcbn/advpub/0/advpub_18-15/_pdf/-char/en | |||||
