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In vitro analysis of radioprotective effect of monoterpenes
https://repo.qst.go.jp/records/49035
https://repo.qst.go.jp/records/49035e0569be8-95a9-4cd2-9b5b-ad5d558ae83e
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-05-17 | |||||
| タイトル | ||||||
| タイトル | In vitro analysis of radioprotective effect of monoterpenes | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kudo, Kenichi
× Kudo, Kenichi× Hanafusa, Tadashi× Ono, Toshiro× 工藤 健一 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Monoterpenes are naturally occurring hydrocarbons composed of two units of isoprenes. They exhibit antioxidant activity to scavenge reactive oxygen species, such as hydroxyl radicals. We investigated the potential of monoterpenes such as thymol, linalool, and menthol to act as radioprotectants. The proliferation of EL4 cells, a mouse lymphoma cell line, treated with linalool at a concentration of 500 μM or more was not affected by X-ray irradiation. Plasmid-nicking assay performed using formamidopyrimidine-DNA glycosylase showed that linalool prevented single strand breaks and oxidized purines on pUC19 plasmid DNA. These findings indicate that linalool has the ability to scavenge reactive oxygen species and is a potential radioprotector. | |||||
| 書誌情報 |
Journal of Radioanalytical and Nuclear Chemistry 巻 313, p. 169-174, 発行日 2017-05 |
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| 出版者 | ||||||
| 出版者 | Springer | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1007/s10967-017-5268-0 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://link.springer.com/article/10.1007/s10967-017-5268-0 | |||||
| 関連名称 | http://link.springer.com/article/10.1007/s10967-017-5268-0 | |||||
