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  1. 原著論文

Measurement of nuclear reaction cross sections by using Cherenkov radiation toward high-precision proton therapy

https://repo.qst.go.jp/records/48836
https://repo.qst.go.jp/records/48836
16f31d3e-839c-44ad-9966-b0cff7164dd1
Item type 学術雑誌論文 / Journal Article(1)
公開日 2018-05-07
タイトル
タイトル Measurement of nuclear reaction cross sections by using Cherenkov radiation toward high-precision proton therapy
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Masuda, Takamitsu

× Masuda, Takamitsu

WEKO 871396

Masuda, Takamitsu

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Kataoka, Jun

× Kataoka, Jun

WEKO 871397

Kataoka, Jun

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Arimoto, Makoto

× Arimoto, Makoto

WEKO 871398

Arimoto, Makoto

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Takabe, Miho

× Takabe, Miho

WEKO 871399

Takabe, Miho

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Nishio, Teiji

× Nishio, Teiji

WEKO 871400

Nishio, Teiji

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Matsushita, Keiichiro

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WEKO 871401

Matsushita, Keiichiro

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Miyake, Tasuku

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WEKO 871402

Miyake, Tasuku

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Yamamoto, Seiichi

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WEKO 871403

Yamamoto, Seiichi

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稲庭, 拓

× 稲庭, 拓

WEKO 871404

稲庭, 拓

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Toshito, Toshiyuki

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WEKO 871405

Toshito, Toshiyuki

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Inaniwa, Taku

× Inaniwa, Taku

WEKO 871406

en Inaniwa, Taku

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抄録
内容記述タイプ Abstract
内容記述 Monitoring the in vivo dose distribution in proton therapy is desirable for the accurate irradiation of a tumor. Although positron emission tomography (PET) is widely used for confirmation, the obtained distribution of positron emitters produced by the protons does not trace the dose distribution due to the different physical processes. To estimate the accurate dose from the PET image, the cross sections of nuclear reactions that produce positron emitters are important yet far from being sufficient. In this study, we measured the cross sections of 16O(p,x)15O, 16O(p,x)13N, and 16O(p,x)11C with a wideenergy range (approximately 5–70 MeV) by observing the temporal evolution of the Cherenkov
radiation emitted from positrons generated via β+ decay along the proton path. Furthermore, we implemented the new cross sectional data into a conventional Monte Carlo (MC) simulation, so that a direct comparison was possible with the PET measurement. We confirmed that our MC results showed good agreement with the experimental data, both in terms of the spatial distributions and temporal
evolutions. Although this is the first attempt at using the Cherenkov radiation in the measurements of nuclear cross sections, the obtained results suggest the method is convenient and widely applicable for high precision proton therapy.
書誌情報 Scientific Reports

巻 8, 発行日 2018-05
出版者
出版者 Nature Publishing Group
ISSN
収録物識別子タイプ ISSN
収録物識別子 2045-2322
DOI
識別子タイプ DOI
関連識別子 10.1038/s41598-018-20906-z
関連サイト
識別子タイプ URI
関連識別子 http://www.nature.com/articles/s41598-018-20906-z
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