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Measurement of nuclear reaction cross sections by using Cherenkov radiation toward high-precision proton therapy
https://repo.qst.go.jp/records/48836
https://repo.qst.go.jp/records/4883616f31d3e-839c-44ad-9966-b0cff7164dd1
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-05-07 | |||||
タイトル | ||||||
タイトル | Measurement of nuclear reaction cross sections by using Cherenkov radiation toward high-precision proton therapy | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Masuda, Takamitsu
× Masuda, Takamitsu× Kataoka, Jun× Arimoto, Makoto× Takabe, Miho× Nishio, Teiji× Matsushita, Keiichiro× Miyake, Tasuku× Yamamoto, Seiichi× 稲庭, 拓× Toshito, Toshiyuki× Inaniwa, Taku |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Monitoring the in vivo dose distribution in proton therapy is desirable for the accurate irradiation of a tumor. Although positron emission tomography (PET) is widely used for confirmation, the obtained distribution of positron emitters produced by the protons does not trace the dose distribution due to the different physical processes. To estimate the accurate dose from the PET image, the cross sections of nuclear reactions that produce positron emitters are important yet far from being sufficient. In this study, we measured the cross sections of 16O(p,x)15O, 16O(p,x)13N, and 16O(p,x)11C with a wideenergy range (approximately 5–70 MeV) by observing the temporal evolution of the Cherenkov radiation emitted from positrons generated via β+ decay along the proton path. Furthermore, we implemented the new cross sectional data into a conventional Monte Carlo (MC) simulation, so that a direct comparison was possible with the PET measurement. We confirmed that our MC results showed good agreement with the experimental data, both in terms of the spatial distributions and temporal evolutions. Although this is the first attempt at using the Cherenkov radiation in the measurements of nuclear cross sections, the obtained results suggest the method is convenient and widely applicable for high precision proton therapy. |
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書誌情報 |
Scientific Reports 巻 8, 発行日 2018-05 |
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出版者 | ||||||
出版者 | Nature Publishing Group | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2045-2322 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1038/s41598-018-20906-z | |||||
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識別子タイプ | URI | |||||
関連識別子 | http://www.nature.com/articles/s41598-018-20906-z |