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Correction of stopping power and LET quenching for radiophotoluminescent glass dosimetry in a therapeutic proton beam
https://repo.qst.go.jp/records/48801
https://repo.qst.go.jp/records/48801cdb72061-b5a1-4e15-b3fe-b4deb6e966f1
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-04-24 | |||||
| タイトル | ||||||
| タイトル | Correction of stopping power and LET quenching for radiophotoluminescent glass dosimetry in a therapeutic proton beam | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
張, 維珊
× 張, 維珊× 古場, 裕介× Katayose, Tetsurou× Yasui, Keisuke× Omachi, Chihiro× Hariu, Masatsugu× Saitoh, Hedetoshi× 張 維珊× 古場 裕介 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To measure the absorbed dose to water D w in proton beams using a radiophotoluminescent glass dosimeter (RGD), a method with the correction for the change of the mass stopping power ratio (SPR) and the linear energy transfer (LET) dependence of radiophotoluminescent efficiency $\varepsilon _{{\rm LET}}^{{\rm RGD}}$ is proposed. \nThe calibration coefficient in terms of D w for RGDs (GD-302M, Asahi Techno Glass) was obtained using a 60Co γ-ray. The SPR of water to the RGD was calculated by Monte Carlo simulation, and $\varepsilon _{{\rm LET}}^{{\rm RGD}}$ was investigated experimentally using a 70 MeV proton beam. For clinical usage, the residual range R res was used as a quality index to determine the correction factor for the beam quality $k_{{\rm Q},{{{\rm Q}}_{0}}}^{{\rm RGD}}$ and the LET quenching effect of the RGD $k_{{\rm LET}}^{{\rm RGD}}$ . The proposed method was evaluated by measuring D w at different depths in a 200 MeV proton beam. \nFor both non-modulated and modulated proton beams, $k_{{\rm Q},{{{\rm Q}}_{0}}}^{{\rm RGD}}$ decreases rapidly where R res is less than 4 cm. The difference in $k_{{\rm Q},{{{\rm Q}}_{0}}}^{{\rm RGD}}$ between a non-modulated and a modulated proton beam is less than 0.5% for the R res range from 0 cm to 22 cm. $\varepsilon _{{\rm LET}}^{{\rm RGD}}$ decreases rapidly at a LET range from 1 to 2 keV µm−1. In the evaluation experiments, D w using RGDs, $D_{{\rm w},{\rm Q}}^{{\rm RGD}}$ showed good agreement with that obtained using an ionization chamber and the relative difference was within 3% where R res was larger than 1 cm. The uncertainty budget for $D_{{\rm w},{\rm Q}}^{{\rm RGD}}$ in a proton beam was estimated to investigate the potential of RGD postal dosimetry in proton therapy. \nThese results demonstrate the feasibility of RGD dosimetry in a therapeutic proton beam and the general versatility of the proposed method. In conclusion, the proposed methodology for RGDs in proton dosimetry is applicable where R res > 1 cm and the RGD is feasible as a postal audit dosimeter for proton therapy. |
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| 書誌情報 |
Physics in Medicine & Biology 巻 62, p. 8869-8881, 発行日 2017-11 |
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| 出版者 | ||||||
| 出版者 | IOP Publishing | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1088/1361-6560/aa9155 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://iopscience.iop.org/article/10.1088/1361-6560/aa9155 | |||||
| 関連名称 | http://iopscience.iop.org/article/10.1088/1361-6560/aa9155 | |||||
