ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "e558f082-a796-414f-8ef2-88ad082616ca"}, "_deposit": {"created_by": 1, "id": "48786", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "48786"}, "status": "published"}, "_oai": {"id": "oai:repo.qst.go.jp:00048786", "sets": ["1"]}, "author_link": ["733686", "733688", "733681", "733689", "733682", "733687", "733685", "733684", "733683"], "item_8_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2018-01", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "561", "bibliographicPageStart": "552", "bibliographicVolumeNumber": "265", "bibliographic_titles": [{"bibliographic_title": "Journal of Neurology"}]}]}, "item_8_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "There is no reliable objective indicator for upper motor neuron dysfunction in amyotrophic lateral sclerosis (ALS). To\ndetermine the clinical significance and potential utility of magnetic resonance (MR) signals, we investigated the relationship\nbetween clinical symptoms and susceptibility changes in the motor cortex measured using susceptibility-weighted MR\nimaging taken by readily available 3-T MRI in clinical practice. Twenty-four ALS patients and 14 control subjects underwent\n3-T MR T1-weighted imaging and susceptibility-weighted MR imaging with the principles of echo-shifting with a train of\nobservations (PRESTO) sequence. We analysed relationships between relative susceptibility changes in the motor cortex\nassessed using voxel-based analysis (VBA) and clinical scores, including upper motor neuron score, ALS functional rating\nscale revised score, and Medical Research Council sum score on physical examination. Patients with ALS exhibited significantly\nlower signal intensity in the precentral gyrus on susceptibility-weighted MR imaging compared with controls. Clinical\nscores were significantly correlated with susceptibility changes. Importantly, the extent of the susceptibility changes in the\nbilateral precentral gyri was significantly correlated with upper motor neuron scores. The results of our pilot study using\nVBA indicated that low signal intensity in motor cortex on susceptibility-weighted MR imaging may correspond to clinical\nsymptoms, particularly upper motor neuron dysfunction. Susceptibility-weighted MR imaging may be a useful diagnostic\ntool as an objective indicator of upper motor neuron dysfunction.", "subitem_description_type": "Abstract"}]}, "item_8_relation_13": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "29356968", "subitem_relation_type_select": "PMID"}}]}, "item_8_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1007/s00415-017-8728-0", "subitem_relation_type_select": "DOI"}}]}, "item_8_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0340-5354 ", "subitem_source_identifier_type": "ISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Endo, Hironobu"}], "nameIdentifiers": [{"nameIdentifier": "733681", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sekiguchi, Kenji"}], "nameIdentifiers": [{"nameIdentifier": "733682", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shimada, Hitoshi"}], "nameIdentifiers": [{"nameIdentifier": "733683", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ueda, Takehiro"}], "nameIdentifiers": [{"nameIdentifier": "733684", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kowa, Hisatomo"}], "nameIdentifiers": [{"nameIdentifier": "733685", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kanda, Fumio"}], "nameIdentifiers": [{"nameIdentifier": "733686", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Toda, Tatsushi"}], "nameIdentifiers": [{"nameIdentifier": "733687", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Endo, Hironobu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "733688", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shimada, Hitoshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "733689", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Low signal intensity in motor cortex on susceptibility-weighted MR imaging is correlated with clinical signs of amyotrophic lateral sclerosis: a pilot study", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Low signal intensity in motor cortex on susceptibility-weighted MR imaging is correlated with clinical signs of amyotrophic lateral sclerosis: a pilot study"}]}, "item_type_id": "8", "owner": "1", "path": ["1"], "permalink_uri": "https://repo.qst.go.jp/records/48786", "pubdate": {"attribute_name": "公開日", "attribute_value": "2018-03-05"}, "publish_date": "2018-03-05", "publish_status": "0", "recid": "48786", "relation": {}, "relation_version_is_last": true, "title": ["Low signal intensity in motor cortex on susceptibility-weighted MR imaging is correlated with clinical signs of amyotrophic lateral sclerosis: a pilot study"], "weko_shared_id": -1}
  1. 原著論文

Low signal intensity in motor cortex on susceptibility-weighted MR imaging is correlated with clinical signs of amyotrophic lateral sclerosis: a pilot study

https://repo.qst.go.jp/records/48786
https://repo.qst.go.jp/records/48786
7c28ce88-cff4-4ac1-9190-41431d976d6b
Item type 学術雑誌論文 / Journal Article(1)
公開日 2018-03-05
タイトル
タイトル Low signal intensity in motor cortex on susceptibility-weighted MR imaging is correlated with clinical signs of amyotrophic lateral sclerosis: a pilot study
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Endo, Hironobu

× Endo, Hironobu

WEKO 733681

Endo, Hironobu

Search repository
Sekiguchi, Kenji

× Sekiguchi, Kenji

WEKO 733682

Sekiguchi, Kenji

Search repository
Shimada, Hitoshi

× Shimada, Hitoshi

WEKO 733683

Shimada, Hitoshi

Search repository
Ueda, Takehiro

× Ueda, Takehiro

WEKO 733684

Ueda, Takehiro

Search repository
Kowa, Hisatomo

× Kowa, Hisatomo

WEKO 733685

Kowa, Hisatomo

Search repository
Kanda, Fumio

× Kanda, Fumio

WEKO 733686

Kanda, Fumio

Search repository
Toda, Tatsushi

× Toda, Tatsushi

WEKO 733687

Toda, Tatsushi

Search repository
Endo, Hironobu

× Endo, Hironobu

WEKO 733688

en Endo, Hironobu

Search repository
Shimada, Hitoshi

× Shimada, Hitoshi

WEKO 733689

en Shimada, Hitoshi

Search repository
抄録
内容記述タイプ Abstract
内容記述 There is no reliable objective indicator for upper motor neuron dysfunction in amyotrophic lateral sclerosis (ALS). To
determine the clinical significance and potential utility of magnetic resonance (MR) signals, we investigated the relationship
between clinical symptoms and susceptibility changes in the motor cortex measured using susceptibility-weighted MR
imaging taken by readily available 3-T MRI in clinical practice. Twenty-four ALS patients and 14 control subjects underwent
3-T MR T1-weighted imaging and susceptibility-weighted MR imaging with the principles of echo-shifting with a train of
observations (PRESTO) sequence. We analysed relationships between relative susceptibility changes in the motor cortex
assessed using voxel-based analysis (VBA) and clinical scores, including upper motor neuron score, ALS functional rating
scale revised score, and Medical Research Council sum score on physical examination. Patients with ALS exhibited significantly
lower signal intensity in the precentral gyrus on susceptibility-weighted MR imaging compared with controls. Clinical
scores were significantly correlated with susceptibility changes. Importantly, the extent of the susceptibility changes in the
bilateral precentral gyri was significantly correlated with upper motor neuron scores. The results of our pilot study using
VBA indicated that low signal intensity in motor cortex on susceptibility-weighted MR imaging may correspond to clinical
symptoms, particularly upper motor neuron dysfunction. Susceptibility-weighted MR imaging may be a useful diagnostic
tool as an objective indicator of upper motor neuron dysfunction.
書誌情報 Journal of Neurology

巻 265, 号 3, p. 552-561, 発行日 2018-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 0340-5354
PubMed番号
識別子タイプ PMID
関連識別子 29356968
DOI
識別子タイプ DOI
関連識別子 10.1007/s00415-017-8728-0
戻る
0
views
See details
Views

Versions

Ver.1 2023-05-15 19:06:13.777654
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3