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Synthesis and Enhanced Radical Scavenging Activity of a Conformationally Constrained Epigallocatechin Analogue
https://repo.qst.go.jp/records/48536
https://repo.qst.go.jp/records/4853691832e5c-bdec-4b2f-8399-68ec9d6a4a7f
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-02-20 | |||||
| タイトル | ||||||
| タイトル | Synthesis and Enhanced Radical Scavenging Activity of a Conformationally Constrained Epigallocatechin Analogue | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Imai, Kohei
× Imai, Kohei× Nakanishi, Ikuo× Anzai, Kazunori× Ozawa, Toshihiko× Miyata, Naoki× Urano, Shiro× Okuda, Haruhiro× Nakamura, Asao× Fukuhara, Kiyoshi× 中西 郁夫× 安西 和紀× 小澤 俊彦 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The freely rotating single bond between the pyrogallol and chroma substructures in epigallocatechin (EGC) was constrained by reaction of EGC with acetone in the presence of trimethylsilyl trifluoromethanesulfonate to prepare the rigidified analogue in good yield. The synthesized analogue was examined for free radical scavenging activity against galvinoxyl radical and found to be 27-fold more potent than EGC. | |||||
| 書誌情報 |
Chemistry Letters 巻 40, 号 12, p. 1417-1419, 発行日 2011-12 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0366-7022 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1246/cl.2011.1417 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.chemistry.or.jp/journals/chem-lett/ | |||||
| 関連名称 | http://www.chemistry.or.jp/journals/chem-lett/ | |||||
