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Irradiation system of ions (H-Xe) for biological studies near the Bragg peak
https://repo.qst.go.jp/records/48448
https://repo.qst.go.jp/records/48448815d0b8d-50f9-49bf-b785-c0f92436a720
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-02-04 | |||||
| タイトル | ||||||
| タイトル | Irradiation system of ions (H-Xe) for biological studies near the Bragg peak | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Konishi, Teruaki
× Konishi, Teruaki× Takeyasu, Akihiro× Yasuda, Nakahiro× Ishizawa, Sachi× Nakajima, Hiroshi× Fujisaki, Takayuki× Furusawa, Yoshiya× Satou, Yukio× Hieda, Kotaro× 小西 輝昭× 竹安 明弘× 安田 仲宏× 石澤 紗智× 中島 宏× 古澤 佳也× 佐藤 幸夫× 檜枝 光太郎 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We have developed a new system for irradiating biological samples in air with ions from H to Xe below 6.0MeV∕nucleon near the Bragg peak. The irradiation system can provide ion beams with 20‐mm diameter of which the central area of 100mm2 is uniform in fluence rate within a standard deviation of ±10%. For each ion, the linear energy transfer is selectable by irradiation positions in air, from the lowest at the surface of a vacuum window to the highest at the Bragg peak, for example, from 281 to 977 keV/μm for C ions. A wide range of fluence rates, 10−3–104ions∕μm2∕s, can be provided by the system, which makes it possible to irradiate a variety of biological samples with different target sizes, from small plasmid DNA to living mammalian cells. The ion fluence irradiated to each sample is calculated from the output of the secondary electron monitor using the linear relationship between the output and ion fluence measured at the sample position by CR-39 track detectors. Survival curves and visualization of NBS1 foci for human cells are presented as examples of preliminary experiments using C ions near the Bragg peak. | |||||
| 書誌情報 |
Review of Scientific Instruments 巻 76, 号 114302, p. 1-6, 発行日 2005-11 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0034-6748 | |||||
