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Impact of Intrafractional Bowel Gas Movement on Carbon Ion Beam Dose Distribution in Pancreatic Radiotherapy
https://repo.qst.go.jp/records/48434
https://repo.qst.go.jp/records/4843467b0d350-808c-47ed-b7dc-bbfba6648650
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-01-11 | |||||
| タイトル | ||||||
| タイトル | Impact of Intrafractional Bowel Gas Movement on Carbon Ion Beam Dose Distribution in Pancreatic Radiotherapy | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kumagai, Motoki
× Kumagai, Motoki× Hara, Ryusuke× Mori, Shinichiro× Yanagi, Takeshi× Asakura, Hiroshi× Kishimoto, Riwa× Katou, Hirotoshi× Yamada, Shigeru× Kandatsu, Susumu× Kamada, Tadashi× 熊谷 始紀× 原 竜介× 森 慎一郎× 柳 剛× 浅倉 裕史× 岸本 理和× 加藤 博敏× 山田 滋× 神立 進× 鎌田 正 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose: We assessed carbon ion beam dose variation due to bowel gas movement in pancreatic radiotherapy. Material and Methods: A total of 10 pancreatic cancer inpatients were subject to diagnostic contrast-enhanced dynamic helical CT examination under breath-holding conditions, which included multiple-phase dynamic CT with arterial, venous and delayed phases. The time increments of the arterial-venous and arterial-delayed phases were 35 and 145 s, respectively. A compensating bolus was designed to cover the target obtained at the arterial phase. Carbon ion dose distribution was calculated by applying the bolus to the CT data sets at the other two phases. Results: Dose conformation to the clinical target volume (CTV) was degraded by beam overshoot/undershoot due to bowel gas movement. The D95 for CTV was degraded from 97.4% (range: 97.1% - 98.1%) of the prescribed dose to 93.1% (range: 85.4% - 97.8%) at 145 s. Excessive dosing to normal tissues varied among tissues, and was for example 12.0 GyE/12.9 GyE (0s/ 145s) for the cord and 38.5 GyE/39.6 GyE (0s/145s) for the duodenum. The magnitude of beam overshoot/undershoot was particularly exacerbated from the anterior and left directions. Conclusions: Bowel gas movement causes dosimetric variation to the target during treatment for radiotherapy. The effect of bowel gas movement varies with beam angle, with greatest influence on the AP and LR beams. |
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| 書誌情報 |
International Journal of Radiation Oncology Biology Physics 巻 73, 号 4, p. 1276-1281, 発行日 2009-03 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0360-3016 | |||||
