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Neural basis for inferring false beliefs and social emotions in others among individuals with schizophrenia and those at ultra-high risk for psychosis.
https://repo.qst.go.jp/records/48213
https://repo.qst.go.jp/records/482136049e54e-b328-4bf2-bb94-4538e65595f4
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-07-26 | |||||
タイトル | ||||||
タイトル | Neural basis for inferring false beliefs and social emotions in others among individuals with schizophrenia and those at ultra-high risk for psychosis. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Takano, Yosuke
× Takano, Yosuke× Aoki, Yuta× Yahata, Noriaki× Kawakubo, Yuki× Inoue, Hideyuki× Iwashiro, Norichika× Natsubori, Tatsunobu× Koike, Shinsuke× Gonoi, Wataru× Sasaki, Hiroki× Takao, Hidemasa× Kasai, Kiyoto× Yamasue, Hidenori× 八幡 憲明 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Inferring beliefs and social emotions of others has different neural substrates and possibly different roles in the pathophysiology of different clinical phases of schizophrenia. The current study investigated the neural basis for inferring others' beliefs and social emotions, as individual concepts, in 17 subjects at ultra-high risk for psychosis (UHR), 16 patients with schizophrenia and 20 healthy controls. Brain activity significantly differed from normal in both the left superior temporal sulcus (STS) and the inferior frontal gyrus (IFG) in the schizophrenia group while inferring others' beliefs, whereas those of UHR group were in the middle of those in the schizophrenia and healthy-control groups. Brain activity during inferring others' social emotions significantly differed in both the left STS and right IFG among individuals at UHR; however, there was no significant difference in the schizophrenia group. In contrast, brain activity differed in the left IFG of those in both the schizophrenia and UHR groups while inferring social emotion. Regarding the difference in direction of the abnormality, both the UHR and schizophrenia groups were characterized by hyper-STS and hypo-IFG activations when inferring others' beliefs and emotions. These findings might reflect different aspects of the same pathophysiological process at different clinical phases of psychosis. | |||||
書誌情報 |
Psychiatry Research 巻 259, p. 34-41, 発行日 2016-11 |
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出版者 | ||||||
出版者 | Elsevier/North-Holland Biomedical Press | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0165-1781 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 27960147 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.pscychresns.2016.11.003 |