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RENEB intercomparisons applying the conventional Dicentric Chromosome Assay (DCA)
https://repo.qst.go.jp/records/48127
https://repo.qst.go.jp/records/481271e349695-2c51-4f77-a9ce-97f88d5600ec
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-07-20 | |||||
| タイトル | ||||||
| タイトル | RENEB intercomparisons applying the conventional Dicentric Chromosome Assay (DCA) | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Oestreicher, Ursula
× Oestreicher, Ursula× Suto, Yumiko× Wojcik, Andrzej× al., et× 數藤 由美子 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose: Two quality controlled inter-laboratory exercises were organized within the EU project ‘Realizing the European Network of Biodosimetry (RENEB)’ to further optimize the dicentric chromosome assay (DCA) and to identify needs for training and harmonization activities within the RENEB network. Materials and methods: The general study design included blood shipment, sample processing, analysis of chromosome aberrations and radiation dose assessment. After manual scoring of dicentric chromosomes in different cell numbers dose estimations and corresponding 95% confidence intervals were submitted by the participants. Results: The shipment of blood samples to the partners in the European Community (EU) were performed successfully. Outside the EU unacceptable delays occurred. The results of the dose estimation demonstrate a very successful classification of the blood samples in medically relevant groups. In comparison to the 1st exercise the 2nd intercomparison showed an improvement in the accuracy of dose estimations especially for the high dose point. Conclusions: In case of a large-scale radiological incident, the pooling of ressources by networks can enhance the rapid classification of individuals in medically relevant treatment groups based on the DCA. The performance of the RENEB network as a whole has clearly benefited from harmonization processes and specific training activities for the network partners. |
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| 書誌情報 |
International Journal of Radiation Biology 巻 93, 号 1, p. 20-29, 発行日 2016-10 |
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| 出版者 | ||||||
| 出版者 | Taylor & Francic | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0955-3002 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1080/09553002.2016.1233370 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.tandfonline.com/doi/full/10.1080/09553002.2016.1233370 | |||||
| 関連名称 | http://www.tandfonline.com/doi/full/10.1080/09553002.2016.1233370 | |||||
