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Gated carbon-ion scanning treatment for pancreatic tumour with field specific target volume and organs at risk.
https://repo.qst.go.jp/records/48092
https://repo.qst.go.jp/records/480925d564590-348e-4fc4-b797-ae7a98461c4d
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-07-13 | |||||
タイトル | ||||||
タイトル | Gated carbon-ion scanning treatment for pancreatic tumour with field specific target volume and organs at risk. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Miki, Kentaro
× Miki, Kentaro× Mori, Shinichiro× Shiomi, Miho× Yamada, Shigeru× 三木 健太朗× 森 慎一郎× 塩見 美帆× 山田 滋 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Objective To assess the feasibility of treatment planning for pancreatic tumours subject to respiratory motion using field-specific target volumes (FTV) and field-specific organs at risk (FOAR) using four-dimensional computed tomography (4DCT). \n Methods Fourteen pancreatic cancer patients underwent 4DCT. Radiation oncologists contoured the gross tumour volume (GTV), clinical target volume (CTV), spinal cord, duodenum, kidneys, and stomach. The gating duty cycle was set to 30 % around exhalation. FTV and FOAR were calculated using the 4DCT dataset. Planning target volumes (PTV) and planning organs at risk volumes (PRV) were defined as equal to FTV and FOAR, respectively. A dose of 55.2 Gy relative biological effectiveness (RBE) was planned to target the PTV from four beam angles. A single field uniform dose (SFUD) plan was selected. The dose distribution, including intrafractional motion changes, was generated. \n Results The mean volume of target receiving 95 % of the planned doses was 96.4 ± 4.1 % to the GTV and 94.7 ± 0.9 % to the CTV. The highest dose to 2 cc of duodenal volume was 27.5 Gy (RBE). The volume of the stomach receiving ⩾30 Gy (RBE) was <7.0 cc in all patients. All metrics for OARs satisfied dose constraints. \n Conclusion Dose to the CTV was covered sufficiently by the 4DCT-generated FTV, and dose to OARs was reduced by 4DCT-generated FOAR. This methodology may prevent adverse reactions while preserving local tumour control. |
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書誌情報 |
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) 巻 32, 号 12, p. 1521-1528, 発行日 2016-11 |
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出版者 | ||||||
出版者 | Istituti Editoriali e Poligrafici Internazionali | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1120-1797 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 27884463 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.ejmp.2016.11.009 | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.physicamedica.com/article/S11797(16)30987-5/fulltext | |||||
関連名称 | http://www.physicamedica.com/article/S11797(16)30987-5/fulltext |