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  1. 原著論文

Gated carbon-ion scanning treatment for pancreatic tumour with field specific target volume and organs at risk.

https://repo.qst.go.jp/records/48092
https://repo.qst.go.jp/records/48092
5d564590-348e-4fc4-b797-ae7a98461c4d
Item type 学術雑誌論文 / Journal Article(1)
公開日 2017-07-13
タイトル
タイトル Gated carbon-ion scanning treatment for pancreatic tumour with field specific target volume and organs at risk.
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Miki, Kentaro

× Miki, Kentaro

WEKO 482917

Miki, Kentaro

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Mori, Shinichiro

× Mori, Shinichiro

WEKO 482918

Mori, Shinichiro

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Shiomi, Miho

× Shiomi, Miho

WEKO 482919

Shiomi, Miho

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Yamada, Shigeru

× Yamada, Shigeru

WEKO 482920

Yamada, Shigeru

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三木 健太朗

× 三木 健太朗

WEKO 482921

en 三木 健太朗

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森 慎一郎

× 森 慎一郎

WEKO 482922

en 森 慎一郎

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塩見 美帆

× 塩見 美帆

WEKO 482923

en 塩見 美帆

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山田 滋

× 山田 滋

WEKO 482924

en 山田 滋

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抄録
内容記述タイプ Abstract
内容記述 Objective
To assess the feasibility of treatment planning for pancreatic tumours subject to respiratory motion using field-specific target volumes (FTV) and field-specific organs at risk (FOAR) using four-dimensional computed tomography (4DCT).
\n Methods
Fourteen pancreatic cancer patients underwent 4DCT. Radiation oncologists contoured the gross tumour volume (GTV), clinical target volume (CTV), spinal cord, duodenum, kidneys, and stomach. The gating duty cycle was set to 30 % around exhalation. FTV and FOAR were calculated using the 4DCT dataset. Planning target volumes (PTV) and planning organs at risk volumes (PRV) were defined as equal to FTV and FOAR, respectively. A dose of 55.2 Gy relative biological effectiveness (RBE) was planned to target the PTV from four beam angles. A single field uniform dose (SFUD) plan was selected. The dose distribution, including intrafractional motion changes, was generated.
\n Results
The mean volume of target receiving 95 % of the planned doses was 96.4 ± 4.1 % to the GTV and 94.7 ± 0.9 % to the CTV. The highest dose to 2 cc of duodenal volume was 27.5 Gy (RBE). The volume of the stomach receiving ⩾30 Gy (RBE) was <7.0 cc in all patients. All metrics for OARs satisfied dose constraints.
\n Conclusion
Dose to the CTV was covered sufficiently by the 4DCT-generated FTV, and dose to OARs was reduced by 4DCT-generated FOAR. This methodology may prevent adverse reactions while preserving local tumour control.
書誌情報 Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

巻 32, 号 12, p. 1521-1528, 発行日 2016-11
出版者
出版者 Istituti Editoriali e Poligrafici Internazionali
ISSN
収録物識別子タイプ ISSN
収録物識別子 1120-1797
PubMed番号
識別子タイプ PMID
関連識別子 27884463
DOI
識別子タイプ DOI
関連識別子 10.1016/j.ejmp.2016.11.009
関連サイト
識別子タイプ URI
関連識別子 http://www.physicamedica.com/article/S11797(16)30987-5/fulltext
関連名称 http://www.physicamedica.com/article/S11797(16)30987-5/fulltext
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