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First demonstration of multi-color 3-D in vivo imaging using ultra-compact Compton camera
https://repo.qst.go.jp/records/48041
https://repo.qst.go.jp/records/480419b9615b5-1dee-4b46-8f7c-6a37e7f58b64
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-06-06 | |||||
| タイトル | ||||||
| タイトル | First demonstration of multi-color 3-D in vivo imaging using ultra-compact Compton camera | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kishimoto, (Waseda University) Aya
× Kishimoto, (Waseda University) Aya× Kataoka, (Waseda University) Jun× Taya, (Waseda University) Takanori× Tagawa, (Waseda University) Leo× Mochizuki, (Waseda University) Saku× Ohsuka, (Hamamatsu Photonics) Shinji× Nagao, Yuto× Kurita, Keisuke× Yamaguchi, Mitsutaka× Kawachi, Naoki× Matsunaga, (Osaka University) Keiko× Ikeda, (Osaka University) Hayato× Shimosegawa, (Osaka University) Eku× Hatazawa, (Osaka University) Jun× 長尾 悠人× 栗田 圭輔× 山口 充孝× 河地 有木 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In the field of nuclear medicine, single photon emission tomography and positron emission tomography are the two most common techniques in molecular imaging, but the available radioactive tracers have been limited either by energy range or difficulties in production and delivery. Thus, the use of a Compton camera, which features gamma-ray imaging of arbitrary energies from a few hundred keV to more than MeV, is eagerly awaited along with potential new tracers which have never been used in current modalities. In this paper, we developed an ultra-compact Compton camera that weighs only 580 g. The camera consists of fine-pixelized Ce-doped Gd3Al2Ga3O12 scintillators coupled with multi-pixel photon counter arrays. We first investigated the 3-D imaging capability of our camera system for a diffuse source of a planar geometry, and then conducted small animal imaging as pre-clinical evaluation. For the first time, we successfully carried out the 3-D color imaging of a live mouse in just 2 h. By using tri-color gamma-ray fusion images, we confirmed that 131I, 85Sr, and 65Zn can be new tracers that concentrate in each target organ. | |||||
| 書誌情報 |
Scientific Reports (Online Only URL:http://www.nature.com/srep/index.html) 巻 7, 号 2110, p. 2110-1-2110-7, 発行日 2017-05 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 2045-2322 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 28522868 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1038/s41598-017-02377-w | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.nature.com/articles/s41598-017-02377-w | |||||
| 関連名称 | https://www.nature.com/articles/s41598-017-02377-w | |||||
