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Cation exchange separation of 61Cu2+ from natCo targets and preparation of 61Cu-DOTA-HSA as a blood pool agent
https://repo.qst.go.jp/records/47689
https://repo.qst.go.jp/records/47689c652c5bb-7a46-4dbe-88ac-8ba753bc4d3e
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-03-27 | |||||
| タイトル | ||||||
| タイトル | Cation exchange separation of 61Cu2+ from natCo targets and preparation of 61Cu-DOTA-HSA as a blood pool agent | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Hao, Guiyang
× Hao, Guiyang× Fukumura, Toshimitsu× Nakao, Ryuji× Suzuki, Hisashi× Ferenc, Szelecsenyi× Kovacs, Zoltan× Suzuki, Kazutoshi× Ｈａｏ Ｇｕｉｙａｎｇ× 福村 利光× 中尾 隆士× 鈴木 寿× Ｆｅｒｅｎｃ Ｓｚｅｌｅｃｓｅｎｙｉ× ゾルタン コバックス× 鈴木 和年 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | An improved method for isolation of (61)Cu(2+) from a (nat)Co target using cation exchange was developed. (61)Cu(2+) was eluted from a cation exchange resin column by 0.2 M HCl with 90% acetone, while Co(2+) remained on the column. The whole separation process was completed within 50 min at more than 72% yield. The Co(2+) impurity level in (61)Cu(2+) solution was reduced to less than 0.1 ppm. Highly pure (61)Cu(2+) solution was then applied to prepare (61)Cu-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA)-human serum albumin (HSA) which showed good blood pool imaging properties. | |||||
| 書誌情報 |
Applied Radiation and Isotopes 巻 67, 号 4, p. 511-515, 発行日 2008-12 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0969-8043 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.apradiso.2008.12.004 | |||||
