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Stability of 11C-labeled PET radiopharmaceuticals
https://repo.qst.go.jp/records/47688
https://repo.qst.go.jp/records/47688341dcdab-fefb-4645-85c5-a8fe44de9b07
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-03-27 | |||||
| タイトル | ||||||
| タイトル | Stability of 11C-labeled PET radiopharmaceuticals | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Fukumura, Toshimitsu
× Fukumura, Toshimitsu× Nakao, Ryuji× Yamaguchi, Masatoshi× Suzuki, Kazutoshi× 福村 利光× 中尾 隆士× 山口 政俊× 鈴木 和年 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The stability of widely used 11C-radiopharmaceuticals was investigated. The purity of many 11C-radiopharmaceuticals was found to be low even at the end of synthesis and to lower with time by radiolysis. Examinations of the effects of radical scavengers showed that the radiopharmaceuticals were classified into four groups: Group 1 showing excellent stability; Group 2 showing suppressed radiolysis in the presence of a selective scavenger of hydroxyl radicals; Group 3 showing suppression in the presence of a selective scavenger of hydrated electrons; Group 4 showing suppression in the presence of both scavengers. Using appropriate additives according to these classes, 11C-radiopharmaceuticals were prepared with excellent radiochemical purity even with high levels of radioactivity and specific activity. | |||||
| 書誌情報 |
Applied Radiation and Isotopes 巻 61, 号 6, p. 1279-1287, 発行日 2004-12 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0969-8043 | |||||
