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Decomposition of an aqueous solution of [11C]Ro 15-4513: implication of hydrated electrons in the radiolysis of[11C]Ro 15-4513
https://repo.qst.go.jp/records/47687
https://repo.qst.go.jp/records/476876665d6f5-5776-463d-a25d-d1fbc7899067
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-03-27 | |||||
| タイトル | ||||||
| タイトル | Decomposition of an aqueous solution of [11C]Ro 15-4513: implication of hydrated electrons in the radiolysis of[11C]Ro 15-4513 | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Fukumura, Toshimitsu
× Fukumura, Toshimitsu× Akaike, Shihoko× Yoshida, Yuichirou× Suzuki, Kazutoshi× 福村 利光× 吉田 勇一郎× 鈴木 和年 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | An aqueous solution of [11C]Ro 15-4513 underwent decomposition to give a few radioactive degradation products. The major degradation product corresponded to that of authentic Ro 15-4513 with 60Co radiolysis, which showed a molecular weight of 301(M+H). The structure of this degradation product was estimated to have an amine group instead of an azido group on Ro 15-4513. Radiolysis of Ro15-4513 was not suppressed by the addition of selective hydroxyl radical scavenger (MeOH,HCOO-), in contrast,it was suppressed effectively in the presence of a selective hydrated electron scavenger (NaNO3), suggesting that hydrated electrons would play an important role in the radiolysis of [11C]Ro 15-4513. | |||||
| 書誌情報 |
Nuclear Medicine and Biology 巻 30, p. 389-395, 発行日 2003-03 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0969-8051 | |||||
