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Induced radioactivity of a GSO scintillator by secondary fragments in carbon ion therapy and its effects on in-beam OpenPET imaging
https://repo.qst.go.jp/records/47558
https://repo.qst.go.jp/records/475588ce94d42-ed4c-41e3-adf2-2119c7668618
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2016-10-05 | |||||
タイトル | ||||||
タイトル | Induced radioactivity of a GSO scintillator by secondary fragments in carbon ion therapy and its effects on in-beam OpenPET imaging | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Hirano, Yoshiyuki
× Hirano, Yoshiyuki× Nitta, Munetaka× Nishikido, Fumihiko× Yoshida, Eiji× Inadama, Naoko× Yamaya, Taiga× 平野 祥之× 新田 宗孝× 錦戸 文彦× 吉田 英治× 稲玉 直子× 山谷 泰賀 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The accumulation of induced radioactivity within in-beam PET scanner scintillators is of concern for its long-term clinical usage in particle therapy. To estimate the effects on OpenPET which we are developing for in-beam PET based on GSOZ (Zi doped Gd2SiO5), we measured the induced radioactivity of GSO activated by secondary fragments in a water phantom irradiation by a 12C beam with an energy of 290 MeV u−1. Radioisotopes of Na, Ce, Eu, Gd, Nd, Pm and Tb including positron emitters were observed in the gamma ray spectra of the activated GSO with a high purity Ge detector and their absolute radioactivities were calculated. We used the Monte Carlo simulation platform, Geant4 in which the observed radioactivity was assigned to the scintillators of a precisely reproduced OpenPET and the single and coincidence rates immediately after one treatment and after one-year usage were estimated for the most severe conditions. Comparing the highest coincidence rate originating from the activated scintillators (background) and the expected coincidence rate from an imaging object (signal), we determined the expected signal-tonoise ratio to be more than 7 within 3 min and more than 10 within 1 min from the scan start time. We concluded the effects of scintillator activation and their accumulation on the OpenPET imaging were small and clinical long-term usage of the OpenPET was feasible. Keywords: in-beam PET, GSO scintillator, particle therapy, openPET, induced radioactivity, secondary fragments (Some figures may appear in colour only in the online journal) |
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書誌情報 |
Physics in medicine and biology 巻 61, 号 13, p. 4870-4889, 発行日 2016-07 |
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出版者 | ||||||
出版者 | IOPscience | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0031-9155 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 27280308 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1088/0031-9155/61/13/4870 | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://iopscience.iop.org/article/10.1088/0031-9155/61/13/4870 | |||||
関連名称 | http://iopscience.iop.org/article/10.1088/0031-9155/61/13/4870 |