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Chemogenetic disconnection of monkey orbitofrontal and rhinal cortex reversibly disrupts reward value.
https://repo.qst.go.jp/records/47538
https://repo.qst.go.jp/records/47538807fee90-a7c3-4ad3-8dd2-f019f25338ce
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-09-05 | |||||
| タイトル | ||||||
| タイトル | Chemogenetic disconnection of monkey orbitofrontal and rhinal cortex reversibly disrupts reward value. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
A, G Eldridge Mark
× A, G Eldridge Mark× Lerchner, Walter× C, Saunders Richard× Kaneko, Hiroyuki× W, Krausz Kristopher× J, Gonzalez Frank× Ji, Bin× Higuchi, Makoto× Minamimoto, Takafumi× J, Richmond Barry× 金子 博之× 季 斌× 樋口 真人× 南本 敬史× リッチモンド バリー |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To study how the interaction between orbitofrontal (OFC) and rhinal (Rh) cortices influences the judgment of reward size, we reversibly disconnected these regions using hM4Di-DREADD (designer receptor exclusively activated by designer drug). Repeated inactivation reduced sensitivity to differences in reward size in two monkeys. These results suggest that retrieval of relative stimulus values from memory depends on the interaction between Rh and OFC | |||||
| 書誌情報 |
nature neuroscience 巻 19, 号 1, p. 37-39, 発行日 2015-12 |
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| 出版者 | ||||||
| 出版者 | Nature Publishing Group | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1097-6256 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 26656645 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | doi:10.1038/nn.4192 | |||||
