ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

  1. 原著論文

Vasodilation mechanism of cerebral microvessels induced by neural activation under high baseline CBF level results from hypercapnia in awake mice

https://repo.qst.go.jp/records/47534
https://repo.qst.go.jp/records/47534
b4a1d3dc-72f3-49fd-9d19-dd9f4c9a111b
Item type 学術雑誌論文 / Journal Article(1)
公開日 2016-09-05
タイトル
タイトル Vasodilation mechanism of cerebral microvessels induced by neural activation under high baseline CBF level results from hypercapnia in awake mice
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Nishino, Asuka

× Nishino, Asuka

WEKO 476335

Nishino, Asuka

Search repository
Takuwa, Hiroyuki

× Takuwa, Hiroyuki

WEKO 476336

Takuwa, Hiroyuki

Search repository
Urushihata, Takuya

× Urushihata, Takuya

WEKO 476337

Urushihata, Takuya

Search repository
Ito, Hiroshi

× Ito, Hiroshi

WEKO 476338

Ito, Hiroshi

Search repository
Ikoma, Yoko

× Ikoma, Yoko

WEKO 476339

Ikoma, Yoko

Search repository
Matsuura, Tetsuya

× Matsuura, Tetsuya

WEKO 476340

Matsuura, Tetsuya

Search repository
西野 明日香

× 西野 明日香

WEKO 476341

en 西野 明日香

Search repository
田桑 弘之

× 田桑 弘之

WEKO 476342

en 田桑 弘之

Search repository
漆畑 拓弥

× 漆畑 拓弥

WEKO 476343

en 漆畑 拓弥

Search repository
伊藤 浩

× 伊藤 浩

WEKO 476344

en 伊藤 浩

Search repository
生駒 洋子

× 生駒 洋子

WEKO 476345

en 生駒 洋子

Search repository
松浦 哲也

× 松浦 哲也

WEKO 476346

en 松浦 哲也

Search repository
抄録
内容記述タイプ Abstract
内容記述 Objective: We investigated the effects of the baseline CBF level at resting state on neurovascular coupling.
Methods: Diameters of arterioles, capillaries, and venulas in awake mouse brain were measured by a two-photon microscope. Vasodilation in each of the cerebral vessels was caused by three experimental conditions: (1) sensory stimulation, (2) 5% CO2 inhalation (hypercapnia), (3) simultaneous exposure to sensory stimulation and 5% CO2 inhalation. CBF and CBV were also measured by a microscope and a CCD camera.
Results: Increases in CBF and CBV were observed under all experimental conditions. After the increases in CBF and CBV due to hypercapnia, additional increases in CBF and CBV occurred during sensory stimulation. Diameter changes in arterioles were significantly larger than those in capillaries and venulas under both sensory stimulation and 5% CO2 inhalation. Additional vasodilation from sensory stimulation was observed under hypercapnia. The diameter change in each vessel type during sensory stimulation was maintained under simultaneous exposure to sensory stimulation and hypercapnia.
Conclusions:The diameter change of cerebral vessels during neural activation is reproducible regardless of whether baseline CBF has increased or not. Our finding directly demonstrates the concept of uncoupling between energy consumption and energy supply during cortical activation
書誌情報 Microcirculation

巻 22, 号 8, p. 744-752, 発行日 2015-11
出版者
出版者 Wiley
DOI
識別子タイプ DOI
関連識別子 doi:10.1111/micc.12250
戻る
0
views
See details
Views

Versions

Ver.1 2023-05-15 23:38:39.651189
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR 2.0
  • OAI-PMH JPCOAR 1.0
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3